⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11181263 | 0.98 | FBP1 (0.48) | — | |
| SCHEMBL6532776 | 0.82 | FBP1 (0.54) | — | |
| SCHEMBL10709338 | 0.80 | FBP1 (0.43) | — | |
| SCHEMBL9586347 | 0.80 | — | — | |
| SCHEMBL3070412 | 0.78 | — | — | |
| SCHEMBL27632300 | 0.78 | FBP1 (0.45) | — | |
| SCHEMBL11327639 | 0.77 | FBP1 (0.48) | — | |
| Potassium Ion SCHEMBL11192203 | 0.77 | FBP1 (0.48) | — | |
| SCHEMBL4339783 | 0.75 | FBP1 (0.42) | — | |
| SCHEMBL28983778 | 0.74 | HPGDS (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1565459-A2 | HETEROARYLSULFONYLMETHYL HYDROXAMIC ACIDS AND AMIDES AND THEIR USE AS PROTEASE INHIBITORS | Pharmacia Corporation (US) | 2005-08-24 | — | — | EP | disclosed |
| WO-2004048368-A2 | HETEROARYLSULFONYLMETHYL HYDROXAMIC ACIDS AND AMIDES AND THEIR USE AS PROTEASE INHIBITORS | PHARMACIA CORPORATION (US) | 2004-06-10 | — | — | WO | disclosed |
| EP-0361961-B1 | Organic componds and their use as pharmaceuticals | LILLY SA (ES) | 1994-02-02 | — | — | EP | disclosed |
| US-5041461-A | Organic compounds and their use as pharmaceuticals | LILLY INDUSTRIES LIMITED (GB) | 1991-08-20 | — | — | US | disclosed |
| EP-0361961-A1 | Organic componds and their use as pharmaceuticals | LILLY S.A. (ES) | 1990-04-04 | — | — | EP | disclosed |