Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.52 |
| ▸ | CES1 | P23141 | 4/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | FNTA | P49354 | 1/20 | 0.48 |
| ▸ | FNTB | P49356 | 1/20 | 0.48 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.43 |
| ▸ | PPARG | P37231 | 6/20 | 0.43 |
| ▸ | PPARD | Q03181 | 6/20 | 0.43 |
| ▸ | PPARA | Q07869 | 6/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TLR2 | O60603 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | FABP4 | P15090 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6206603 | 1.00 | CES2 (0.52) | CES2CES1THRBFNTAFNTB | |
| SCHEMBL6206613 | 0.85 | CES2 (0.52) | CES2CES1THRBFNTAFNTB | |
| SCHEMBL8401708 | 0.77 | FNTA (0.63) | CES2CES1THRBFNTAFNTB | |
| SCHEMBL8401710 | 0.77 | FNTA (0.63) | CES2CES1THRBFNTAFNTB | |
| SCHEMBL277151 | 0.76 | FNTA (0.57) | CES2CES1THRBFNTAFNTB | |
| SCHEMBL9840247 | 0.75 | FNTA (0.67) | CES2CES1THRBFNTAFNTB | |
| SCHEMBL9839424 | 0.75 | FNTA (0.67) | CES2CES1THRBFNTAFNTB | |
| SCHEMBL9330854 | 0.75 | FNTA (0.67) | CES2CES1THRBFNTAFNTB | |
| SCHEMBL8944801 | 0.75 | FNTA (0.67) | CES2CES1THRBFNTAFNTB | |
| SCHEMBL9840255 | 0.75 | FNTA (0.67) | CES2CES1THRBFNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532128-A1 | INHIBITORS OF HCV NS5B POLYMERASE | Pharmacia & Upjohn Company LLC (US) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002977-A1 | INHIBITORS OF HCV NS5B POLYMERASE | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-01-08 | — | — | WO | disclosed |