Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1141274 | 0.92 | GAA (0.56) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL1726035 | 0.90 | GAA (0.55) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| Lithium SCHEMBL7065338 | 0.90 | GAA (0.55) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| Potassium SCHEMBL7063916 | 0.90 | GAA (0.55) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL1086028 | 0.85 | KMT2A (0.56) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL14650156 | 0.85 | ALDH1A1 (0.51) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL1720659 | 0.83 | KMT2A (0.54) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL13359464 | 0.83 | GAA (0.49) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL10925924 | 0.82 | MAPT (0.56) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL6205874 | 0.82 | ESR1 (0.49) | NPC1RAB9ATSHRCYP1A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1298133-B1 | Procedure for the alkylation of 3,4-dihydroxythiophene-2,5-dicarboxylic esters | BAYER CHEMICALS AG (DE) | 2005-01-19 | — | — | EP | claimed |
| US-6750354-B2 | ALKYLATION OF 3,4- DIHYDROXYTHIOPHENE-2, 5-DICARBOXYLIC ESTERS OR THEIR ALKALI METAL OR ALKALINE EARTH METAL SALTS WITH ALKYLATING AGENTS IN A POLAR DILUENT IN THE PRESENCE OF QUATERNARY ONIUM SALTS | BAYER AKTIENGESELLSCHAFT (DE) | 2004-06-15 | — | — | US | claimed |
| US-20030097007-A1 | Process for the alkylation of 3,4-dihydroxythiophene-2,5-dicarboxylic esters | H. C. STARCK GMBH (DE) | 2003-05-22 | — | — | US | claimed |
| US-6750354-B2 | ALKYLATION OF 3,4- DIHYDROXYTHIOPHENE-2, 5-DICARBOXYLIC ESTERS OR THEIR ALKALI METAL OR ALKALINE EARTH METAL SALTS WITH ALKYLATING AGENTS IN A POLAR DILUENT IN THE PRESENCE OF QUATERNARY ONIUM SALTS | BAYER AKTIENGESELLSCHAFT (DE) | 2004-06-15 | — | — | US | disclosed |
| US-20030097007-A1 | Process for the alkylation of 3,4-dihydroxythiophene-2,5-dicarboxylic esters | H. C. STARCK GMBH (DE) | 2003-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030097007-A1 | Process for the alkylation of 3,4-dihydroxythiophene-2,5-dicarboxylic esters | DIMT1, AS3MT, DDT | ALDH1A1 915/4885KMT2A 195/4885MAPT 1684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.