Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.43 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7829097 | 0.87 | HDAC1 (0.49) | GAAPOLB | |
| SCHEMBL7819170 | 0.86 | ALDH1A1 (0.51) | POLB | |
| SCHEMBL2686767 | 0.84 | MEN1 (0.41) | POLB | |
| SCHEMBL7424934 | 0.83 | FNTA (0.44) | — | |
| SCHEMBL7214284 | 0.82 | ALDH1A1 (0.38) | GAA | |
| SCHEMBL7214111 | 0.80 | F10 (0.50) | GAA | |
| SCHEMBL7213622 | 0.79 | F10 (0.51) | GAA | |
| SCHEMBL16874684 | 0.78 | ERCC1 (0.48) | GAAERCC1ERCC4 | |
| SCHEMBL1543163 | 0.78 | KDM4E (0.44) | GAAERCC1ERCC4 | |
| SCHEMBL16874683 | 0.78 | ERCC1 (0.48) | GAAERCC1ERCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1553085-A1 | Cyclic amine derivatives and their use as drugs | TEIJIN LIMITED (JP) | 2005-07-13 | — | — | EP | disclosed |
| EP-1535909-A2 | Cyclic amine derivatives and their use as drugs | TEIJIN LIMITED (JP) | 2005-06-01 | — | — | EP | disclosed |
| US-6451842-B1 | Cyclic amine derivatives and their use as drugs | DUPONT PHARMACEUTICALS COMPANY | 2002-09-17 | — | — | US | disclosed |
| US-6410566-B1 | ATHEROSCLEROSIS; ANTIARTHRITIC AGENTS | TEIJIN LIMITED (JP) | 2002-06-25 | — | — | US | disclosed |
| US-6362177-B1 | INHIBITION OF CHEMOKINE BINDING | TEIJIN LIMITED (JP) | 2002-03-26 | — | — | US | disclosed |