Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 10/20 | 0.44 |
| ▸ | FNTB | P49356 | 10/20 | 0.44 |
| ▸ | PGGT1B | P53609 | 8/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.44 |
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8833260 | 0.85 | SIRT2 (0.55) | KCNH2DPP4DPP8EPHX1 | |
| SCHEMBL7426687 | 0.85 | SIRT2 (0.55) | KCNH2DPP4DPP8EPHX1 | |
| SCHEMBL7419118 | 0.85 | SIRT2 (0.55) | KCNH2DPP4DPP8EPHX1 | |
| SCHEMBL6206674 | 0.83 | GAA (0.53) | — | |
| SCHEMBL7829097 | 0.82 | HDAC1 (0.49) | CYP2C9KMT2A | |
| SCHEMBL7417913 | 0.82 | SIRT2 (0.35) | FNTAFNTBPGGT1BKCNH2DPP4 | |
| SCHEMBL8042725 | 0.82 | SIRT2 (0.35) | FNTAFNTBPGGT1BDPP4 | |
| SCHEMBL8040065 | 0.82 | TNKS (0.43) | KCNH2DPP4DPP8CYP1A2TSHR | |
| SCHEMBL8029685 | 0.82 | SIRT2 (0.35) | FNTAFNTBPGGT1BKCNH2DPP4 | |
| SCHEMBL8029146 | 0.82 | SIRT2 (0.35) | FNTAFNTBPGGT1BDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853618-A4 | SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHONE POULENC RORER PHARMA (US) | 2000-03-15 | — | — | EP | disclosed |
| EP-0853618-A1 | SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) | 1998-07-22 | — | — | EP | disclosed |
| US-5612353-A | ANTICOAGULANT | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1997-03-18 | — | — | US | disclosed |
| WO-1996040679-A1 | SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N-[(AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHÔNE-POULENC RORER PHARMACEUTICALS INC. (US) | 1996-12-19 | — | — | WO | disclosed |