Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6193672 | 0.80 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1GAAKDM4EMAPK1 | |
| SCHEMBL1520901 | 0.77 | MAPT (0.39) | SMN1; SMN2ALDH1A1GAAKDM4EMAPK1 | |
| SCHEMBL24349342 | 0.77 | MAPT (0.46) | SMN1; SMN2ALDH1A1GAAKDM4EMAPK1 | |
| SCHEMBL5710844 | 0.77 | ALDH1A1 (0.37) | SMN1; SMN2ALDH1A1GAAKDM4EMAPK1 | |
| SCHEMBL21226326 | 0.68 | KMT2A (0.44) | SMN1; SMN2ALDH1A1GAAKDM4EMAPK1 | |
| SCHEMBL24349372 | 0.64 | KMT2A (0.41) | SMN1; SMN2ALDH1A1GAAKDM4EMAPK1 | |
| SCHEMBL13686001 | 0.64 | NOX1 (0.44) | SMN1; SMN2ALDH1A1GAAKDM4EMAPK1 | |
| SCHEMBL17333584 | 0.63 | MAPT (0.70) | SMN1; SMN2ALDH1A1GAAKDM4EMAPK1 | |
| SCHEMBL24349346 | 0.62 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1GAAKDM4EMAPK1 | |
| SCHEMBL24349354 | 0.62 | MEN1 (0.43) | SMN1; SMN2ALDH1A1GAAKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1292268-B1 | AGENT FOR DYEING KERATIN CONTAINING FIBERS | HENKEL KGAA (DE) | 2005-02-23 | — | — | EP | disclosed |