SCHEMBL24349372

SCHEMBL24349372

CC1(C)c2cc3ccccc3cc2-c2nc3ccccc3nc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.41
RAB9A P51151 4/20 0.40
NPC1 O15118 3/20 0.40
NQO2 P16083 2/20 0.39
ALDH1A1 P00352 7/20 0.36
SMN1; SMN2 Q16637 6/20 0.36
HPGD P15428 2/20 0.36
KDM4E B2RXH2 6/20 0.36
MAPT P10636 4/20 0.36
GAA P10253 2/20 0.36
PKM P14618 2/20 0.36
POLB P06746 1/20 0.36
HSD17B10 Q99714 3/20 0.35
MAPK1 P28482 2/20 0.35
GLA P06280 1/20 0.35
HTT P42858 1/20 0.35
CDK5 Q00535 1/20 0.35
CDK5R1 Q15078 1/20 0.35
MEN1 O00255 2/20 0.34
TP53 P04637 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24349335 0.84 MAPK14 (0.35) KMT2ARAB9ANPC1ALDH1A1
SCHEMBL24349371 0.81 KMT2A (0.49) KMT2ARAB9ANPC1NQO2ALDH1A1
SCHEMBL21226326 0.81 KMT2A (0.44) KMT2ARAB9ANPC1ALDH1A1SMN1; SMN2
SCHEMBL21667629 0.76 L3MBTL1 (0.41) KMT2ARAB9ANPC1NQO2ALDH1A1
SCHEMBL24349342 0.76 MAPT (0.46) KMT2ARAB9ANPC1NQO2ALDH1A1
SCHEMBL12726547 0.74 ALDH1A1 (0.50) KMT2ARAB9ANPC1NQO2ALDH1A1
SCHEMBL16062617 0.73 ALDH1A1 (0.41) KMT2AALDH1A1HPGDHSD17B10MAPK1
SCHEMBL22186542 0.73 KMT2A (0.42) KMT2ARAB9ANPC1NQO2ALDH1A1
SCHEMBL21667416 0.72 L3MBTL1 (0.47) KMT2AALDH1A1SMN1; SMN2KDM4EMAPT
SCHEMBL21226327 0.72 MAPT (0.52) KMT2ARAB9ANPC1NQO2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220081510-A1 THERMOPLASTIC RESIN, OPTICAL FILM MADE THEREFROM, DIOL COMPOUND, DIESTER COMPOUND MITSUBISHI CHEMICAL CORPORATION (JP) 2022-03-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220081510-A1 THERMOPLASTIC RESIN, OPTICAL FILM MADE THEREFROM, DIOL COMPOUND, DIESTER COMPOUND RTF1, RNF10, RAD51 KMT2A 525/4885RAB9A 2868/4885NPC1 3378/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.