Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 2/20 | 0.39 |
| ▸ | FES | P07332 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | MARK3 | P27448 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | PTAFR | P25105 | 5/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6030971 | 0.91 | ALDH1A1 (0.44) | CYP3A4FAAHFLT4FESRET | |
| SCHEMBL6029645 | 0.84 | ALDH1A1 (0.49) | CYP3A4FAAHFLT4FESRET | |
| SCHEMBL6030084 | 0.81 | CHRM4 (0.45) | FAAHFLT4FESRETMARK3 | |
| SCHEMBL16643981 | 0.78 | ALDH1A1 (0.59) | CYP3A4ALDH1A1KDM4EMEN1LMNA | |
| SCHEMBL6030667 | 0.78 | NPC1 (0.46) | CYP3A4ALDH1A1KDM4EMEN1LMNA | |
| SCHEMBL6030651 | 0.78 | NPC1 (0.46) | CYP3A4ALDH1A1KDM4EMEN1GAA | |
| SCHEMBL6031608 | 0.77 | ALDH1A1 (0.47) | CYP3A4FAAHFLT4CDK2ALDH1A1 | |
| SCHEMBL6029757 | 0.76 | ALDH1A1 (0.43) | ALDH1A1KDM4EMEN1LMNAMAPT | |
| SCHEMBL6030054 | 0.76 | ALDH1A1 (0.43) | ALDH1A1KDM4EMEN1LMNAMAPT | |
| SCHEMBL6029710 | 0.76 | ALDH1A1 (0.43) | ALDH1A1KDM4EMEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1467978-A4 | PANCREATIC LIPASE INHIBITOR COMPOUNDS, THEIR SYNTHESIS AND USE | OSI PHARM INC (US) | 2005-11-02 | — | — | EP | disclosed |
| EP-1467978-A1 | PANCREATIC LIPASE INHIBITOR COMPOUNDS, THEIR SYNTHESIS AND USE | OSI Pharmaceuticals, Inc. (US) | 2004-10-20 | — | — | EP | disclosed |
| WO-2003053944-A1 | PANCREATIC LIPASE INHIBITOR COMPOUNDS, THEIR SYNTHESIS AND USE | OSI PHARMACEUTICALS, INC. (US) | 2003-07-03 | — | — | WO | disclosed |