Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.40 |
| ▸ | PTAFR | P25105 | 6/20 | 0.40 |
| ▸ | FLT4 | P35916 | 2/20 | 0.40 |
| ▸ | FES | P07332 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | MARK3 | P27448 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6029645 | 0.93 | ALDH1A1 (0.49) | ALDH1A1HPGDSMN1; SMN2CYP3A4FAAH | |
| SCHEMBL6206773 | 0.91 | CYP3A4 (0.42) | ALDH1A1CYP3A4CHRM4FAAHPTAFR | |
| SCHEMBL6030084 | 0.88 | CHRM4 (0.45) | ALDH1A1HPGDSMN1; SMN2CHRM4FAAH | |
| SCHEMBL6030651 | 0.87 | NPC1 (0.46) | ALDH1A1HPGDSMN1; SMN2CYP3A4NPC1 | |
| SCHEMBL6030667 | 0.87 | NPC1 (0.46) | ALDH1A1HPGDSMN1; SMN2CYP3A4NPC1 | |
| SCHEMBL6029757 | 0.85 | ALDH1A1 (0.43) | ALDH1A1HPGDPKMRAB9AMEN1 | |
| SCHEMBL6030054 | 0.85 | ALDH1A1 (0.43) | ALDH1A1HPGDPKMRAB9AMEN1 | |
| SCHEMBL6029669 | 0.85 | ALDH1A1 (0.43) | ALDH1A1HPGDPKMRAB9AMEN1 | |
| SCHEMBL6029710 | 0.85 | ALDH1A1 (0.43) | ALDH1A1HPGDPKMRAB9AMEN1 | |
| SCHEMBL6031178 | 0.85 | ALDH1A1 (0.43) | ALDH1A1HPGDPKMRAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7064122-B2 | Pancreatic lipase inhibitor compounds, their synthesis and use | OSI PHARMACEUTICALS, INC. (US) | 2006-06-20 | — | — | US | disclosed |
| US-20030195199-A1 | Pancreatic lipase inhibitor compounds, their synthesis and use | OSI PHARMACEUTICALS, INC. | 2003-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030195199-A1 | Pancreatic lipase inhibitor compounds, their synthesis and use | PNLIP, LIPC, CEL | ALDH1A1 1832/4885HPGD 4273/4885SMN1; SMN2 1723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.