Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 8/20 | 0.38 |
| ▸ | CCNC | P24863 | 5/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.36 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.36 |
| ▸ | CDK19 | Q9BWU1 | 3/20 | 0.36 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.36 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | DRD3 | P35462 | 3/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4480929 | 0.81 | HRH3 (0.38) | CDK8CCNCKCNH2CDK19MAP4K2 | |
| SCHEMBL5305790 | 0.77 | CCR5 (0.43) | SLC22A12CDK8CCNCKCNH2CDK19 | |
| SCHEMBL4497675 | 0.77 | DRD2 (0.39) | SLC22A12CDK8CCNCKCNH2CDK19 | |
| SCHEMBL4497667 | 0.77 | DRD2 (0.39) | SLC22A12CDK8CCNCKCNH2CDK19 | |
| SCHEMBL5308578 | 0.76 | KCNH2 (0.49) | CDK8CCNCKCNH2KCNJ1IRAK4 | |
| SCHEMBL5305787 | 0.73 | CCR3 (0.42) | SLC22A12CDK8CCNCKCNH2CDK19 | |
| SCHEMBL3400497 | 0.73 | CDK8 (0.49) | SLC22A12CDK8CCNCCDK19IRAK4 | |
| SCHEMBL14610965 | 0.71 | CDK8 (0.42) | CDK8CCNCKCNH2CDK19MAP4K2 | |
| SCHEMBL4495204 | 0.70 | DRD2 (0.51) | CDK8CCNCKCNH2IRAK4DRD2 | |
| SCHEMBL13921377 | 0.69 | KCNH2 (0.48) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583537-A3 | PIPERIDINE COMPOUNDS AS ANTIBACTERIALS | GLAXO GROUP LIMITED (GB) | 2005-12-14 | — | — | EP | disclosed |
| EP-1583537-A2 | PIPERIDINE COMPOUNDS AS ANTIBACTERIALS | GLAXO GROUP LIMITED (GB) | 2005-10-12 | — | — | EP | disclosed |
| WO-2004002490-A2 | PIPERIDINE COMPOUNDS AS ANTIBACTERIALS | GLAXO GROUP LIMITED (GB) | 2004-01-08 | — | — | WO | disclosed |