Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 2/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10054253 | 0.67 | LIMK1 (0.57) | LIMK1CLK1 | |
| SCHEMBL1809291 | 0.60 | CA12 (0.31) | — | |
| SCHEMBL21315925 | 0.59 | LIMK1 (0.36) | LIMK1CLK1 | |
| SCHEMBL17051494 | 0.59 | LIMK1 (0.49) | LIMK1CLK1 | |
| SCHEMBL27174136 | 0.59 | GPR3 (0.54) | LIMK1CLK1 | |
| SCHEMBL149872 | 0.59 | GPR3 (0.54) | LIMK1CLK1 | |
| SCHEMBL19486448 | 0.58 | LIMK1 (0.35) | LIMK1CLK1 | |
| SCHEMBL9836884 | 0.58 | LIMK1 (0.59) | LIMK1CLK1 | |
| SCHEMBL9050404 | 0.58 | LIMK1 (0.43) | LIMK1CLK1 | |
| SCHEMBL8121883 | 0.58 | LIMK1 (0.43) | LIMK1CLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546134-A1 | PIPERAZINE SUBSTITUTED ARYL BENZODIAZEPINES | ELI LILLY AND COMPANY (US) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004014895-A1 | PIPERAZINE SUBSTITUTED ARYL BENZODIAZEPINES | ELI LILLY AND COMPANY (US) | 2004-02-19 | — | — | WO | disclosed |