Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17510055 | 1.00 | POLB (0.48) | POLBHTTTDP1APEX1THRB | |
| SCHEMBL65218 | 0.96 | POLB (0.51) | POLBHTTTDP1APEX1THRB | |
| SCHEMBL31351511 | 0.95 | POLB (0.52) | POLBHTTTDP1APEX1THRB | |
| SCHEMBL19770676 | 0.95 | POLB (0.52) | POLBHTTTDP1APEX1THRB | |
| SCHEMBL4453444 | 0.95 | POLB (0.52) | POLBHTTTDP1APEX1THRB | |
| SCHEMBL17867710 | 0.91 | POLB (0.50) | POLBHTTTDP1APEX1THRB | |
| Methacrylic Acid SCHEMBL21715147 | 0.91 | POLB (0.52) | POLBHTTTDP1APEX1THRB | |
| SCHEMBL14173142 | 0.91 | POLB (0.56) | POLBHTTTDP1APEX1THRB | |
| SCHEMBL59813 | 0.91 | POLB (0.56) | POLBHTTTDP1APEX1THRB | |
| SCHEMBL21034777 | 0.90 | KDM4E (0.53) | POLBHTTTDP1APEX1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2700394-B1 | Use of a solvent-free adhesion promoter to create an adhesive bond between dental composites and the surface of dental frameworks made of high-performance polymers | KULZER & CO GMBH (DE) | 2020-09-09 | — | — | EP | disclosed |
| EP-2113237-B1 | Dental materials with anti-plaque agents | HERAEUS KULZER GMBH (DE) | 2014-12-10 | — | — | EP | disclosed |
| EP-2700394-A2 | Dental adhesive for high performance polymers | Heraeus Kulzer GmbH (DE) | 2014-02-26 | — | — | EP | disclosed |
| EP-2603192-A2 | USE OF SILICIC ACID(S) FOR IMPROVING THE PROPERTIES OF DENTAL MATERIALS AND CORRESPONDING METHOD | Heraeus Kulzer GmbH (DE) | 2013-06-19 | — | — | EP | disclosed |
| US-8431407-B2 | Temperature/irradiation/polymerization indicators | HERAEUS KULZER GMBH (DE) | 2013-04-30 | — | — | US | disclosed |
| WO-2012019735-A2 | USE OF SILICIC ACID(S) FOR IMPROVING THE PROPERTIES OF DENTAL MATERIALS AND CORRESPONDING METHOD | HERAEUS KULZER GMBH (DE) | 2012-02-16 | — | — | WO | disclosed |
| EP-2113237-A1 | Dental materials with anti-plaque agents | Heraeus Kulzer GmbH (DE) | 2009-11-04 | — | — | EP | disclosed |
| EP-1734057-B1 | Temperature, irradiation or polymerization indicators | HERAEUS KULZER GMBH (DE) | 2009-03-25 | — | — | EP | disclosed |
| EP-1734057-A2 | Temperature, irradiation or polymerization indicators | Heraeus Kulzer GmbH (DE) | 2006-12-20 | — | — | EP | disclosed |
| US-20060280649-A1 | Temperature/irradiation/polymerization indicators | HERAEUS KULZER GMBH (DE) | 2006-12-14 | — | — | US | disclosed |