SCHEMBL65218

SCHEMBL65218

C=C(C)C(=O)OCCOc1ccc(C(C)(C)c2ccc(OC(=O)C(=C)C)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.51
HTT P42858 2/20 0.51
TDP1 Q9NUW8 2/20 0.51
APEX1 P27695 1/20 0.51
KDM4E B2RXH2 9/20 0.44
ELANE P08246 1/20 0.43
ALDH1A1 P00352 7/20 0.43
KMT2A Q03164 4/20 0.43
MEN1 O00255 3/20 0.43
SMN1; SMN2 Q16637 3/20 0.42
GAA P10253 1/20 0.41
ATM Q13315 1/20 0.41
LMNA P02545 2/20 0.41
AR P10275 1/20 0.40
THRB P10828 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17510055 0.96 POLB (0.48) POLBHTTTDP1APEX1KDM4E
SCHEMBL620722 0.96 POLB (0.48) POLBHTTTDP1APEX1KDM4E
SCHEMBL17867710 0.95 POLB (0.50) POLBHTTTDP1APEX1KDM4E
SCHEMBL14173142 0.94 POLB (0.56) POLBHTTTDP1APEX1KDM4E
SCHEMBL59813 0.94 POLB (0.56) POLBHTTTDP1APEX1KDM4E
Propane SCHEMBL9476274 0.92 HTT (0.53) POLBHTTTDP1APEX1KDM4E
SCHEMBL11965797 0.90 POLB (0.52) POLBHTTTDP1APEX1KDM4E
SCHEMBL4453444 0.90 POLB (0.52) POLBHTTTDP1APEX1KDM4E
Methacrylic Acid SCHEMBL4236287 0.90 POLB (0.56) POLBHTTTDP1APEX1KDM4E
SCHEMBL19770676 0.90 POLB (0.52) POLBHTTTDP1APEX1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12384870-B2 Method for setting polymerization condition and method for manufacturing optical material MITSUI CHEMICALS, INC. (JP) 2025-08-12 US disclosed
US-12252586-B2 Method for setting conditions for use of polymerization catalyst, polymerization condition setting method, and method for manufacturing optical material MITSUI CHEMICALS, INC. (JP) 2025-03-18 US disclosed
EP-3722840-B1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, AND MOLDED ARTICLE MITSUI CHEMICALS INC (JP) 2024-12-04 EP disclosed
EP-3521907-B1 PHOTOCHROMIC LENS AND POLYMERIZABLE COMPOSITION MITSUI CHEMICALS INC (JP) 2024-12-04 EP disclosed
US-20220372229-A1 METHOD FOR SETTING CONDITIONS FOR USE OF POLYMERIZATION CATALYST, POLYMERIZATION CONDITION SETTING METHOD, AND METHOD FOR MANUFACTURING OPTICAL MATERIAL MITSUI CHEMICALS, INC. (JP) 2022-11-24 US disclosed
CN-109689698-B Polymerizable composition for optical material and molded article 三井化学株式会社 2022-05-31 CN disclosed
EP-3988602-A1 USE CONDITION SETTING METHOD FOR POLYMERIZATION CATALYST, POLYMERIZATION CONDITION SETTING METHOD, AND METHOD FOR PRODUCING OPTICAL MATERIAL Mitsui Chemicals, Inc. (JP) 2022-04-27 EP disclosed
EP-3521322-B1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIALS, AND MOLDED BODY MITSUI CHEMICALS INC (JP) 2022-03-09 EP disclosed
US-11248077-B2 Polymerizable composition for optical material and molded product MITSUI CHEMICALS, INC. (JP) 2022-02-15 US disclosed
CN-113993905-A Method for setting use condition of polymerization catalyst, method for setting polymerization condition, and method for producing optical material 三井化学株式会社 2022-01-28 CN disclosed
EP-2783674-A2 A dental material set and a dental membrane for obscuring a metal color of a dental metal, and a preparing method thereof KABUSHIKI KAISHA SHOFU (JP) 2014-10-01 EP disclosed
US-8455564-B2 Dental composition and composite resin KURARAY NORITAKE DENTAL INC. (JP) 2013-06-04 US disclosed
US-8129443-B2 Inorganic oxide nanoparticles having an X-ray contrast property and high transparency, a functionalized silanediol monomeric or oligomeric surface modifier, and a polymerizable compound; dental composites SUN MEDICAL CO., LTD. (JP) 2012-03-06 US disclosed
US-8124669-B2 Dental composition KURARAY MEDICAL INC. (JP) 2012-02-28 US disclosed
US-20110046261-A1 DENTAL COMPOSITION AND COMPOSITE RESIN KURARAY MEDICAL INC. (JP) 2011-02-24 US disclosed
EP-2275076-A1 DENTAL COMPOSITION AND COMPOSITE RESIN Kuraray Medical Inc. (JP) 2011-01-19 EP disclosed
US-20110003267-A1 DENTAL COMPOSITION KURARAY MEDICAL INC. (JP) 2011-01-06 US disclosed
US-20100081728-A1 Mixable and color tone freely reproducible dental coloring material composition, and set and method thereof KABUSHIKI KAISHA SHOFU 2010-04-01 US disclosed
EP-2119425-A1 DENTAL COMPOSITION Kuraray Medical Inc. (JP) 2009-11-18 EP disclosed
US-20050123762-A1 Polymerizable composition, cured object obtained therefrom, and composite material SUN MEDICAL CO., LTD. (JP) 2005-06-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110046261-A1 DENTAL COMPOSITION AND COMPOSITE RESIN CAD, KATNAL2, ZYX POLB 623/4885HTT 1173/4885TDP1 2992/4885
US-20110003267-A1 DENTAL COMPOSITION NLRP3, TAS2R42, CAD POLB 353/4885HTT 704/4885TDP1 1855/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.