Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4453444 | 0.96 | POLB (0.52) | POLBHTTTDP1APEX1KDM4E | |
| SCHEMBL19770676 | 0.96 | POLB (0.52) | POLBHTTTDP1APEX1KDM4E | |
| SCHEMBL31351511 | 0.96 | POLB (0.52) | POLBHTTTDP1APEX1KDM4E | |
| Methacrylic Acid SCHEMBL4236287 | 0.96 | POLB (0.56) | POLBHTTTDP1APEX1KDM4E | |
| SCHEMBL21034777 | 0.94 | KDM4E (0.53) | POLBHTTTDP1APEX1KDM4E | |
| SCHEMBL59813 | 0.92 | POLB (0.56) | POLBHTTTDP1APEX1KDM4E | |
| SCHEMBL14173142 | 0.92 | POLB (0.56) | POLBHTTTDP1APEX1KDM4E | |
| SCHEMBL17510055 | 0.91 | POLB (0.48) | POLBHTTTDP1APEX1KDM4E | |
| SCHEMBL620722 | 0.91 | POLB (0.48) | POLBHTTTDP1APEX1KDM4E | |
| SCHEMBL13636413 | 0.91 | POLB (0.48) | POLBHTTTDP1APEX1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230059534-A1 | AESTHETIC DENTAL FILLING MATERIAL HAVING HIGH CURING DEPTH | IVOCLAR VIVADENT AG (LI) | 2023-02-23 | — | — | US | claimed |
| US-20230052305-A1 | Esthetic Dental Filling Material With High Depth Of Cure | IVOCLAR VIVADENT AG (LI) | 2023-02-16 | — | — | US | disclosed |
| US-20200054423-A1 | Monochromatic Dental Shaped Article And Blank For Making Dental Restorations | IVOCLAR VIVADENT AG (LI) | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230059534-A1 | AESTHETIC DENTAL FILLING MATERIAL HAVING HIGH CURING DEPTH | CAD, RAD51, REV1 | POLB 619/4885HTT 608/4885TDP1 1544/4885 |
| US-20230052305-A1 | Esthetic Dental Filling Material With High Depth Of Cure | RARA, RARG, RARB | POLB 1392/4885HTT 2416/4885TDP1 2355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.