Lupinifolin

Lupinifolin

SCHEMBL6207285

CC(C)=CCc1c2c(c(O)c3c1OC(c1ccc(O)cc1)CC3=O)C=CC(C)(C)O2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 2/20 0.68
▸ KMT2A Q03164 2/20 0.68
▸ MEN1 O00255 1/20 0.68
▸ POLB P06746 1/20 0.68
▸ XBP1 P17861 1/20 0.68
▸ ODC1 P11926 3/20 0.67
▸ ESR1 P03372 4/20 0.62
▸ ESR2 Q92731 2/20 0.62
▸ AKR1B10 O60218 2/20 0.62
▸ AKR1B1 P15121 2/20 0.62
▸ CACNA1G O43497 2/20 0.62
▸ CACNA1H O95180 2/20 0.62
▸ ABCG2 Q9UNQ0 2/20 0.62
▸ MAOA P21397 1/20 0.62
▸ PDE5A O76074 1/20 0.62
▸ PDPK1 O15530 1/20 0.57
▸ PRKCA P17252 1/20 0.57
▸ BACE1 P56817 1/20 0.57
▸ PRKCQ Q04759 1/20 0.57
▸ CTSK P43235 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29442951 0.93 ODC1 (0.65) MAPTKMT2AMEN1POLBXBP1
Flemichin D SCHEMBL31753877 0.88 IDO1 (0.70) MAPTKMT2AMEN1POLBXBP1
SCHEMBL31717386 0.86 ODC1 (0.65) ODC1ESR1ESR2AKR1B10AKR1B1
SCHEMBL29425338 0.86 ODC1 (0.65) MAPTKMT2AMEN1POLBXBP1
Minimiflorin SCHEMBL5461834 0.86 ODC1 (0.60) MAPTKMT2AMEN1POLBXBP1
Khonklonginol H SCHEMBL31753875 0.83 ODC1 (0.64) ODC1ESR1AKR1B10AKR1B1ABCG2
Lupinifolinol SCHEMBL6668491 0.83 PTPN1 (0.50) MAPTKMT2AMEN1POLBXBP1
Lonchocarpol A SCHEMBL31091681 0.81 MAPT (1.00) MAPTKMT2AMEN1POLBXBP1
Lonchocarpol A SCHEMBL144276 0.81 MAPT (1.00) MAPTKMT2AMEN1POLBXBP1
Lonchocarpol A SCHEMBL144277 0.81 MAPT (1.00) MAPTKMT2AMEN1POLBXBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106770839-B The extraction detection method of flavone compound in a kind of subprostrate sophora 浙江工业大学 2019-04-09 — — CN claimed
CN-106770839-A The extraction detection method of flavone compound in a kind of subprostrate sophora 浙江工业大学 2017-05-31 — — CN claimed
WO-2004028548-A2 INHIBITORS OF THE NITRIX OXIDE SYNTHASE III (NOS III) AS NEUROPROTECTIVE AGENTS CARBOMER, INC. (US) 2004-04-08 — — WO claimed
US-20040063612-A1 Neuroprotective agents CARBOMER, INC. 2004-04-01 — — US claimed
CN-121221586-A Use of flavanone compounds in treating pulmonary fibrosis and acute lung injury 成都大学 2025-12-30 — — CN disclosed
WO-2024189607-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR DISEASES TREATMENT DIDENKO KIRILL (MX) 2024-09-19 — — WO disclosed
CN-106770839-B The extraction detection method of flavone compound in a kind of subprostrate sophora 浙江工业大学 2019-04-09 — — CN disclosed
CN-106770839-A The extraction detection method of flavone compound in a kind of subprostrate sophora 浙江工业大学 2017-05-31 — — CN disclosed
EP-1591112-A1 BREAST CANCER-RESISTANT PROTEIN INHIBITOR Kabushiki Kaisha Yakult Honsha (JP) 2005-11-02 — — EP disclosed
WO-2004028548-A2 INHIBITORS OF THE NITRIX OXIDE SYNTHASE III (NOS III) AS NEUROPROTECTIVE AGENTS CARBOMER, INC. (US) 2004-04-08 — — WO disclosed
US-20040063612-A1 Neuroprotective agents CARBOMER, INC. 2004-04-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040063612-A1 Neuroprotective agents GAP43, NLN, NOS3 MAPT 282/4885KMT2A 4465/4885MEN1 3927/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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