Lonchocarpol A

Lonchocarpol A

SCHEMBL144276

CC(C)=CCc1c(O)c(CC=C(C)C)c2c(c1O)C(=O)CC(c1ccc(O)cc1)O2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 1.00
KMT2A Q03164 2/20 1.00
MEN1 O00255 1/20 1.00
POLB P06746 1/20 1.00
XBP1 P17861 1/20 1.00
ABCG2 Q9UNQ0 5/20 0.80
ESR1 P03372 4/20 0.76
ESR2 Q92731 2/20 0.76
CACNA1G O43497 2/20 0.76
CACNA1H O95180 2/20 0.76
AKR1B10 O60218 2/20 0.76
AKR1B1 P15121 2/20 0.76
MAOA P21397 1/20 0.76
PDE5A O76074 1/20 0.76
IDO1 P14902 1/20 0.74
MAPK1 P28482 1/20 0.70
ATM Q13315 1/20 0.70
NPSR1 Q6W5P4 1/20 0.70
PDPK1 O15530 1/20 0.68
PRKCA P17252 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lonchocarpol A SCHEMBL31091681 1.00 MAPT (1.00) MAPTKMT2AMEN1POLBXBP1
Lonchocarpol A SCHEMBL144277 1.00 MAPT (1.00) MAPTKMT2AMEN1POLBXBP1
SCHEMBL7993201 0.91 MAPT (0.84) MAPTKMT2AMEN1POLBXBP1
SCHEMBL8175342 0.91 MAPT (0.84) MAPTKMT2AMEN1POLBXBP1
SCHEMBL8002908 0.91 MAPT (0.84) MAPTKMT2AMEN1POLBXBP1
SCHEMBL30766285 0.91 MAPT (0.84) MAPTKMT2AMEN1POLBXBP1
SCHEMBL24075554 0.91 MAPT (0.83) MAPTKMT2AMEN1POLBXBP1
SCHEMBL31570921 0.89 ABCG2 (1.00) MAPTKMT2AMEN1POLBXBP1
SCHEMBL16212472 0.88 MAPT (0.78) MAPTKMT2AMEN1POLBXBP1
SCHEMBL29851740 0.88 MAPT (0.78) MAPTKMT2AMEN1POLBXBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11234918-B2 Methods for botanical and/or algae extraction BASF CORPORATION (US) 2022-02-01 US claimed
US-20190046469-A1 COMPOSITIONS AND METHODS FOR TREATING MOOD DISORDERS OR SKIN DISEASE OR DAMAGE KUHRTS ERIC HAUSER (US) 2019-02-14 US claimed
EP-2858641-B1 IMPROVED METHODS FOR BOTANICAL AND/OR ALGAE EXTRACTION BASF CORP (US) 2017-09-06 EP claimed
US-20150209307-A1 COMPOSITIONS AND METHODS FOR TREATING MOOD DISORDERS OR SKIN DISEASE OR DAMAGE KUHRTS ERIC HAUSER (US) 2015-07-30 US claimed
US-20150140141-A1 METHODS FOR BOTANICAL AND/OR ALGAE EXTRACTION BASF BEAUTY CARE SOLUTIONS FRANCE SAS (FR) 2015-05-21 US claimed
EP-2858641-A1 IMPROVED METHODS FOR BOTANICAL AND/OR ALGAE EXTRACTION BASF Corporation (US) 2015-04-15 EP claimed
WO-2014025989-A1 COMPOSITIONS AND METHODS FOR TREATING MOOD DISORDERS OR SKIN DISEASE OR DAMAGE KUHRTS ERIC HAUSER (US) 2014-02-13 WO claimed
US-20140045904-A1 NIACIN FORMULATIONS AND METHODS WITH REDUCED FLUSHING SIDE EFFECT KUHRTS ERIC HAUSER (US) 2014-02-13 US claimed
WO-2013184884-A1 IMPROVED METHODS FOR BOTANICAL AND/OR ALGAE EXTRACTION BASF CORPORATION (US) 2013-12-12 WO claimed
WO-2012051107-A2 NIACIN FORMULATIONS AND METHODS WITH REDUCED FLUSHING SIDE-EFFECT KUHRTS ERIC HAUSER (US) 2012-04-19 WO claimed
US-20120059052-A1 PRENYLFLAVONOID FORMULATIONS BIOACTIVES, INC. (US) 2012-03-08 US claimed
US-20110003888-A1 HOPS EXTRACTION METHODS AND MIXTURES BIOACTIVES, INC. (US) 2011-01-06 US claimed
US-20090209654-A1 Prenylflavonoid Formulations BIOACTIVES, INC. 2009-08-20 US claimed
WO-2008095189-A1 METHODS AND COMPOSITIONS FOR TREATING DYSLIPIDAEMIA BIOACTIVES, INC. (US) 2008-08-07 WO claimed
WO-2008089137-A1 HOPS EXTRACTION METHODS AND MIXTURES BIOACTIVES, INC. (US) 2008-07-24 WO claimed
EP-1909584-A2 PRENYLFLAVONOID FORMULATIONS Bioactives, Inc. (US) 2008-04-16 EP claimed
US-20070218155-A1 Methods and compositions for treating dyslipidaemia BIOACTIVES, INC. 2007-09-20 US claimed
WO-2007016578-A2 PRENYLFLAVONOID FORMULATIONS BIOACTIVES, INC. (US) 2007-02-08 WO claimed
US-20050032882-A1 Botanical extract compositions and methods of use ACTIVEPHYTO TECHNOLOGIES LIMITED (GB) 2005-02-10 US claimed
WO-2004080474-A1 BOTANICAL EXTRACT COMPOSITIONS WITH ANTI-CANCER OR PHYTOESTROGENIC ACTIVITY COMPRISING PRENYL FLAVONOIDS THE MEDICAL RESEARCH AND EDUCATION TRUST (US) 2004-09-23 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11234918-B2 Methods for botanical and/or algae extraction ALG1, ALG8, CUTA MAPT 196/4885KMT2A 4341/4885MEN1 862/4885
US-20120059052-A1 PRENYLFLAVONOID FORMULATIONS TP53, CYP46A1, HPGD MAPT 3025/4885KMT2A 4141/4885MEN1 1161/4885
US-20150209307-A1 COMPOSITIONS AND METHODS FOR TREATING MOOD DISORDERS OR SKIN DISEASE OR DAMAGE CUTA, PSEN2, PNN MAPT 52/4885KMT2A 1595/4885MEN1 1504/4885
US-20190046469-A1 COMPOSITIONS AND METHODS FOR TREATING MOOD DISORDERS OR SKIN DISEASE OR DAMAGE CUTA, PSEN2, PNN MAPT 52/4885KMT2A 1595/4885MEN1 1504/4885
US-20110003888-A1 HOPS EXTRACTION METHODS AND MIXTURES HMGB2, HMGB3, HPGDS MAPT 2474/4885KMT2A 4616/4885MEN1 1381/4885
US-20150140141-A1 METHODS FOR BOTANICAL AND/OR ALGAE EXTRACTION ALG1, ALG8, CUTA MAPT 196/4885KMT2A 4341/4885MEN1 862/4885
US-20050032882-A1 Botanical extract compositions and methods of use CYP19A1, ESR1, GPER1 MAPT 3534/4885KMT2A 2139/4885MEN1 865/4885
US-20140045904-A1 NIACIN FORMULATIONS AND METHODS WITH REDUCED FLUSHING SIDE EFFECT NAPRT, NISCH, NAMPT MAPT 2446/4885KMT2A 3746/4885MEN1 2093/4885
US-20090209654-A1 Prenylflavonoid Formulations TP53, CYP46A1, HPGD MAPT 3025/4885KMT2A 4141/4885MEN1 1161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.