Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.56 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.55 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6210482 | 0.99 | RAB9A (0.57) | RAB9ANPC1SMN1; SMN2POLBMAOB | |
| Hydrochloric Acid SCHEMBL6207459 | 0.99 | RAB9A (0.57) | RAB9ANPC1SMN1; SMN2POLBMAOB | |
| SCHEMBL6208081 | 0.86 | RAB9A (0.59) | RAB9ANPC1SMN1; SMN2POLBMAOB | |
| SCHEMBL6207298 | 0.86 | RAB9A (0.59) | RAB9ANPC1SMN1; SMN2POLBMAOB | |
| Hydrochloric Acid SCHEMBL6207662 | 0.85 | MEN1 (0.55) | RAB9ANPC1SMN1; SMN2POLBMAOB | |
| SCHEMBL6208904 | 0.85 | RAB9A (0.58) | RAB9ANPC1SMN1; SMN2POLBMAOB | |
| SCHEMBL6210392 | 0.85 | RAB9A (0.58) | RAB9ANPC1SMN1; SMN2POLBMAOB | |
| Hydrochloric Acid SCHEMBL6540579 | 0.82 | CA1 (0.53) | RAB9ANPC1SMN1; SMN2POLBPARP10 | |
| SCHEMBL3619364 | 0.81 | LTA4H (0.64) | RAB9ANPC1SMN1; SMN2MAOBPARP10 | |
| SCHEMBL28423110 | 0.81 | MAOB (0.61) | RAB9ANPC1SMN1; SMN2POLBMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583749-A1 | OXAZOLE DERIVATIVES AS INHIBITORS OF CYCLOOXYGENASE | Astellas Pharma Inc. (JP) | 2005-10-12 | — | — | EP | disclosed |
| WO-2004065374-A1 | OXAZOLE DERIVATIVES AS INHIBITORS OF CYCLOOXYGENASE | ASTELLAS PHARMA INC. (JP) | 2004-08-05 | — | — | WO | disclosed |