Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 12/20 | 0.49 |
| ▸ | KIF23 | Q02241 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.35 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.35 |
| ▸ | ACP1 | P24666 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6209231 | 0.93 | KIF11 (0.53) | KIF11KIF23BCHE | |
| SCHEMBL3966803 | 0.82 | KIF11 (0.68) | KIF11KIF23 | |
| SCHEMBL3958220 | 0.82 | KIF11 (0.63) | KIF11KIF23 | |
| SCHEMBL3957584 | 0.82 | KIF11 (0.57) | KIF11KIF23 | |
| SCHEMBL6209979 | 0.82 | KIF11 (0.54) | KIF11KIF23 | |
| SCHEMBL4035977 | 0.81 | KIF11 (0.67) | KIF11KIF23 | |
| SCHEMBL3961576 | 0.81 | KIF11 (0.57) | KIF11KIF23 | |
| Hydrochloric Acid SCHEMBL4046491 | 0.80 | KIF11 (0.66) | KIF11KIF23 | |
| SCHEMBL6207373 | 0.79 | KIF11 (0.53) | KIF11KIF23 | |
| SCHEMBL3959159 | 0.77 | KIF11 (0.60) | KIF11KIF23 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1601673-A1 | NOVEL FUSED HETEROCYCLES AND USES THEREOF | AstraZeneca AB (SE) | 2005-12-07 | — | — | EP | claimed |
| WO-2004078758-A1 | NOVEL FUSED HETEROCYCLES AND USES THEREOF | ASTRAZENECA AB (SE) | 2004-09-16 | — | — | WO | claimed |