Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | DRD4 | P21917 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4846139 | 1.00 | SIGMAR1 (0.60) | SIGMAR1ALDH1A1CYP2C19SMN1; SMN2DRD4 | |
| SCHEMBL4846164 | 1.00 | SIGMAR1 (0.60) | SIGMAR1ALDH1A1CYP2C19SMN1; SMN2DRD4 | |
| SCHEMBL7408973 | 0.93 | BACE1 (0.56) | SIGMAR1ALDH1A1CYP2C19SMN1; SMN2DRD4 | |
| SCHEMBL7401888 | 0.93 | BACE1 (0.56) | SIGMAR1ALDH1A1CYP2C19SMN1; SMN2DRD4 | |
| SCHEMBL17152610 | 0.93 | BACE1 (0.56) | SIGMAR1ALDH1A1CYP2C19SMN1; SMN2DRD4 | |
| SCHEMBL17152549 | 0.88 | SIGMAR1 (0.57) | SIGMAR1ALDH1A1CYP2C19SMN1; SMN2DRD4 | |
| SCHEMBL17152225 | 0.88 | SIGMAR1 (0.61) | SIGMAR1ALDH1A1CYP2C19SMN1; SMN2DRD4 | |
| SCHEMBL4848461 | 0.88 | SIGMAR1 (0.65) | SIGMAR1ALDH1A1CYP2C19SMN1; SMN2DRD4 | |
| SCHEMBL17152245 | 0.87 | SIGMAR1 (0.62) | SIGMAR1ALDH1A1CYP2C19KMT2APOLB | |
| SCHEMBL17152596 | 0.87 | SIGMAR1 (0.59) | SIGMAR1ALDH1A1CYP2C19SMN1; SMN2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100418951-C | Cycloamine derivative and its use as medicine | TEIJIN KASEI LTD (JP) | 2008-09-17 | — | — | CN | disclosed |
| CN-1240699-C | Therapeutic or prophylactic agent for chemokine-associated diseases | TEIJIN LTD (JP) | 2006-02-08 | — | — | CN | disclosed |
| CN-1660815-A | Cyclic amine derivatives and their use as drugs | TEIJIN LTD (JP) | 2005-08-31 | — | — | CN | disclosed |
| EP-1553085-A1 | Cyclic amine derivatives and their use as drugs | TEIJIN LIMITED (JP) | 2005-07-13 | — | — | EP | disclosed |
| EP-1535909-A2 | Cyclic amine derivatives and their use as drugs | TEIJIN LIMITED (JP) | 2005-06-01 | — | — | EP | disclosed |
| CN-1496981-A | Cyclic amine derivatives and their use as pharmaceuticals | ������������ʽ���� | 2004-05-19 | — | — | CN | disclosed |
| US-6451842-B1 | Cyclic amine derivatives and their use as drugs | DUPONT PHARMACEUTICALS COMPANY | 2002-09-17 | — | — | US | disclosed |
| US-6410566-B1 | ATHEROSCLEROSIS; ANTIARTHRITIC AGENTS | TEIJIN LIMITED (JP) | 2002-06-25 | — | — | US | disclosed |
| US-6362177-B1 | INHIBITION OF CHEMOKINE BINDING | TEIJIN LIMITED (JP) | 2002-03-26 | — | — | US | disclosed |
| CN-1279668-A | Cyclic amine derivatives and their use as pharmaceuticals | TEIJIN LTD (JP) | 2001-01-10 | — | — | CN | disclosed |