Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | DRD4 | P21917 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | DRD2 | P14416 | 1/20 | 0.61 |
| ▸ | DRD3 | P35462 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3306841 | 0.89 | SIGMAR1 (0.68) | SIGMAR1ALDH1A1CYP2C19SMN1; SMN2DRD4 | |
| SCHEMBL25541740 | 0.88 | ALDH1A1 (0.53) | SIGMAR1ALDH1A1CYP2C19SMN1; SMN2 | |
| SCHEMBL4846139 | 0.88 | SIGMAR1 (0.60) | SIGMAR1ALDH1A1CYP2C19SMN1; SMN2DRD4 | |
| SCHEMBL4846164 | 0.88 | SIGMAR1 (0.60) | SIGMAR1ALDH1A1CYP2C19SMN1; SMN2DRD4 | |
| SCHEMBL6207514 | 0.88 | SIGMAR1 (0.60) | SIGMAR1ALDH1A1CYP2C19SMN1; SMN2DRD4 | |
| SCHEMBL29712058 | 0.87 | SIGMAR1 (0.65) | SIGMAR1ALDH1A1CYP2C19SMN1; SMN2DRD4 | |
| SCHEMBL2317579 | 0.86 | SIGMAR1 (0.64) | SIGMAR1ALDH1A1DRD4KMT2ADRD2 | |
| SCHEMBL3960091 | 0.86 | SIGMAR1 (0.64) | SIGMAR1ALDH1A1DRD4KMT2ADRD2 | |
| Hydrochloric Acid SCHEMBL4198661 | 0.85 | SIGMAR1 (0.62) | SIGMAR1ALDH1A1DRD4KMT2ADRD2 | |
| Benzene SCHEMBL10799860 | 0.85 | SIGMAR1 (0.62) | SIGMAR1ALDH1A1CYP2C19SMN1; SMN2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7390830-B1 | Remedies or prophylactics for diseases in association with chemokines | TEIJIN LIMITED (JP) | 2008-06-24 | — | — | US | disclosed |
| EP-1179341-B1 | REMEDIES OR PREVENTIVES FOR DISEASES IN ASSOCIATION WITH CHEMOKINES | TEIJIN LTD (JP) | 2005-11-09 | — | — | EP | disclosed |
| EP-1553085-A1 | Cyclic amine derivatives and their use as drugs | TEIJIN LIMITED (JP) | 2005-07-13 | — | — | EP | disclosed |
| EP-1535909-A2 | Cyclic amine derivatives and their use as drugs | TEIJIN LIMITED (JP) | 2005-06-01 | — | — | EP | disclosed |
| US-6451842-B1 | Cyclic amine derivatives and their use as drugs | DUPONT PHARMACEUTICALS COMPANY | 2002-09-17 | — | — | US | disclosed |
| US-6410566-B1 | ATHEROSCLEROSIS; ANTIARTHRITIC AGENTS | TEIJIN LIMITED (JP) | 2002-06-25 | — | — | US | disclosed |
| US-6362177-B1 | INHIBITION OF CHEMOKINE BINDING | TEIJIN LIMITED (JP) | 2002-03-26 | — | — | US | disclosed |
| EP-1179341-A1 | REMEDIES OR PREVENTIVES FOR DISEASES IN ASSOCIATION WITH CHEMOKINES | TEIJIN LIMITED (JP) | 2002-02-13 | — | — | EP | disclosed |