Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 7/20 | 0.59 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.52 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4850736 | 0.91 | CCR2 (0.55) | CCR2HTR4HDAC3HDAC4HDAC1 | |
| SCHEMBL4845881 | 0.91 | CCR2 (0.63) | CCR2HTR4DRD2DRD4DRD3 | |
| SCHEMBL6206317 | 0.88 | CCR2 (0.74) | CCR2HTR4KCNH2CACNA1I | |
| SCHEMBL4847407 | 0.85 | CCR2 (0.59) | CCR2HTR4HDAC3HDAC4HDAC1 | |
| SCHEMBL6205584 | 0.85 | CCR2 (0.63) | CCR2HTR4HDAC3HDAC4HDAC1 | |
| SCHEMBL4847632 | 0.84 | CCR2 (0.59) | CCR2HTR4HDAC3HDAC4HDAC1 | |
| SCHEMBL4843005 | 0.84 | CCR2 (0.54) | CCR2HTR4DRD2DRD4DRD3 | |
| SCHEMBL4840620 | 0.83 | HTR4 (0.58) | CCR2HTR4DRD2DRD4DRD3 | |
| SCHEMBL4844643 | 0.83 | CCR2 (0.67) | CCR2HTR4DRD2DRD4DRD3 | |
| SCHEMBL4845789 | 0.82 | CCR2 (0.55) | CCR2HTR4DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1553085-A1 | Cyclic amine derivatives and their use as drugs | TEIJIN LIMITED (JP) | 2005-07-13 | — | — | EP | claimed |
| EP-1535909-A2 | Cyclic amine derivatives and their use as drugs | TEIJIN LIMITED (JP) | 2005-06-01 | — | — | EP | claimed |
| US-6410566-B1 | ATHEROSCLEROSIS; ANTIARTHRITIC AGENTS | TEIJIN LIMITED (JP) | 2002-06-25 | — | — | US | claimed |