⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11372977 | 0.79 | KMT2A (0.50) | — | |
| SCHEMBL7029411 | 0.78 | — | — | |
| SCHEMBL1523123 | 0.74 | — | — | |
| SCHEMBL418184 | 0.74 | — | — | |
| SCHEMBL106510 | 0.74 | — | — | |
| SCHEMBL12050277 | 0.74 | CRBN (0.34) | — | |
| Pulegone SCHEMBL3064832 | 0.74 | PTPN2 (0.35) | — | |
| SCHEMBL5608629 | 0.74 | CRBN (0.34) | — | |
| Pulegone SCHEMBL58181 | 0.74 | PTPN2 (0.35) | — | |
| Pulegone SCHEMBL38305 | 0.74 | PTPN2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114634442-A | Preparation method of tetrahydrocarbazolone compound | 内蒙古民族大学 | 2022-06-17 | — | — | CN | disclosed |
| CN-110835321-B | Triketone compound containing quinoxaline structure, preparation method and application thereof | 东北农业大学 | 2020-11-24 | — | — | CN | disclosed |
| CN-107446099-B | High-pressure-resistant polyurethane material and preparation method thereof | 上海天原集团胜德塑料有限公司 | 2020-07-14 | — | — | CN | disclosed |
| CN-110835321-A | Triketone compound containing quinoxaline structure, preparation method and application thereof | 东北农业大学 | 2020-02-25 | — | — | CN | disclosed |
| US-10428044-B2 | 3-amino-1,5,6,7-tetrahydro-4H-indol-4-ones | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2019-10-01 | — | — | US | disclosed |
| EP-3157914-B1 | 3-AMINO-1,5,6,7-TETRAHYDRO-4H-INDOL-4-ONES | Bayer Pharma AG (DE) | 2018-09-26 | — | — | EP | disclosed |
| EP-3157914-A1 | 3-AMINO-1,5,6,7-TETRAHYDRO-4H-INDOL-4-ONES | Bayer Pharma Aktiengesellschaft (DE) | 2017-04-26 | — | — | EP | disclosed |
| US-20170101391-A1 | 3-AMINO-1,5,6,7-TETRAHYDRO-4H-INDOL-4-ONES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-04-13 | — | — | US | disclosed |
| WO-2015193339-A1 | 3-AMINO-1,5,6,7-TETRAHYDRO-4H-INDOL-4-ONES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-12-23 | — | — | WO | disclosed |
| US-8501498-B2 | Mass tags for quantitative analyses | DH TECHNOLOGIES DEVELOPMENT PTE. LTD. (SG) | 2013-08-06 | — | — | US | disclosed |
| US-20050004130-A1 | New metabotropic glutamate receptor compounds | ASTRAZENECA AND NPS PHARMACEUTICALS, INC. | 2005-01-06 | — | — | US | disclosed |
| WO-2004069813-A1 | SATURATED QUINOXALINE DERIVATIVES AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR LIGANDS | ASTRAZENECA AB (SE) | 2004-08-19 | — | — | WO | disclosed |
| US-20040152592-A1 | Process for producing carbonyl or hydroxy compound | SUMITOMO CHEMICAL COMPANY, LIMTED | 2004-08-05 | — | — | US | disclosed |
| US-6703528-B2 | CATALYTIC OXIDATION OF OLEFIN | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-03-09 | — | — | US | disclosed |
| EP-1188735-A1 | Process for producing carbonyl or hydroxy compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-03-20 | — | — | EP | disclosed |
| US-20020025906-A1 | Process for producing carbonyl or hydroxy compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-02-28 | — | — | US | disclosed |
| US-5986106-A | Process for preparing 4-substituted-1H-indole-3-glyoxamides | ELI LILLY AND COMPANY (US) | 1999-11-16 | — | — | US | disclosed |
| WO-1999000360-A1 | PROCESS FOR PREPARING 4-SUBSTITUTED-1H-INDOLE-3-GLYOXAMIDES | ELI LILLY AND COMPANY (US) | 1999-01-07 | — | — | WO | disclosed |
| EP-0887342-A2 | Process for preparing 4-substituted-1H-indole-3-glyoxamides | ELI LILLY AND COMPANY (US) | 1998-12-30 | — | — | EP | disclosed |
| US-4434290-A | TREATMENT OF LEUKEMIAS | AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (FR) | 1984-02-28 | — | — | US | disclosed |