Pulegone

Pulegone

SCHEMBL3064832

CC(C)=C1CC[C@H](C)CC1=O

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PTPN2 P17706 1/20 0.35
PTPN1 P18031 1/20 0.35
ALDH1A1 P00352 6/20 0.35
HPGD P15428 4/20 0.35
HTT P42858 1/20 0.35
CRBN Q96SW2 1/20 0.34
KDM4E B2RXH2 2/20 0.34
MAPT P10636 1/20 0.34
ALOX15 P16050 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TLR4 O00206 2/20 0.33
NPC1 O15118 3/20 0.33
RAB9A P51151 3/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
PDK1 Q15118 1/20 0.31
NFE2L2 Q16236 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pulegone SCHEMBL38305 1.00 PTPN2 (0.35) PTPN2PTPN1ALDH1A1HPGDHTT
Pulegone SCHEMBL58181 1.00 PTPN2 (0.35) PTPN2PTPN1ALDH1A1HPGDHTT
Pulegone SCHEMBL8836781 0.98 ALDH1A1 (0.34) PTPN2PTPN1ALDH1A1HPGDHTT
Pulegone SCHEMBL9292430 0.98 PTPN2 (0.38) PTPN2PTPN1ALDH1A1HPGDHTT
Pulegone SCHEMBL8836768 0.98 ALDH1A1 (0.34) PTPN2PTPN1ALDH1A1HPGDHTT
Pulegone SCHEMBL23752046 0.98 ALDH1A1 (0.34) PTPN2PTPN1ALDH1A1HPGDHTT
Pulegone SCHEMBL8196865 0.88 CYP1A2 (0.36) PTPN1ALDH1A1HPGDKDM4ENPC1
Pulegone SCHEMBL6517913 0.86
Pulegone SCHEMBL17963980 0.82 TLR4 (0.31) TLR4NPC1
Pulegone SCHEMBL17064214 0.82 TLR4 (0.31) TLR4NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025090945-A1 FORMULATIONS HAVING A GLYCOSIDE AND A LIPOPHILIC COMPONENT SPOKE SCIENCES, INC. (US) 2025-05-01 WO disclosed
EP-4440556-A2 PARTICLES, AQUEOUS DISPERSIONS, AND LIQUID COMPOSITIONS HAVING HIGH LIPOPHILIC COMPONENT CONCENTRATIONS AND LIPOPHILIC COMPONENT TO SURFACTANT RATIOS Spoke Sciences, Inc. (US) 2024-10-09 EP disclosed
US-20240285549-A1 CANNABIS OIL COMPOSITIONS AND METHODS FOR PREPARATION THEREOF CONSTANCE THERAPEUTICS, INC. (US) 2024-08-29 US disclosed
EP-4402126-A1 AHR AGONISTS Eli Lilly and Company (US) 2024-07-24 EP disclosed
US-20240216456-A1 ENRICHED MINERAL PITCH RESIN PRODUCTS AND METHODS OF MANUFACTURING ENRICHED MINERAL PITCH RESIN PRODUCTS RIZUN NODARI (US) 2024-07-04 US disclosed
US-20240216457-A1 ENRICHED MINERAL PITCH RESIN PRODUCTS AND METHODS OF MANUFACTURING ENRICHED MINERAL PITCH RESIN PRODUCTS RIZUN NODARI (US) 2024-07-04 US disclosed
US-20240207344-A1 ENRICHED MINERAL PITCH RESIN PRODUCTS AND METHODS OF MANUFACTURING ENRICHED MINERAL PITCH RESIN PRODUCTS RIZUN NODARI (US) 2024-06-27 US disclosed
US-20240207343-A1 ENRICHED MINERAL PITCH RESIN PRODUCTS AND METHODS OF MANUFACTURING ENRICHED MINERAL PITCH RESIN PRODUCTS RIZUN NODARI (US) 2024-06-27 US disclosed
US-20240207342-A1 ENRICHED MINERAL PITCH RESIN PRODUCTS AND METHODS OF MANUFACTURING ENRICHED MINERAL PITCH RESIN PRODUCTS RIZUN NODARI (US) 2024-06-27 US disclosed
CN-118215654-A AHR agonists 伊莱利利公司 2024-06-18 CN disclosed
CN-101612360-B Medicine for treating hepatitis, hepatocirrhosis and liver cancer JIAHUI XIAO 2010-07-21 CN disclosed
US-20100167036-A1 SOLID POLYMERIC MATERIALS FOR DETECTION, TRANSFER, AMPLIFICATION AND MEMORY OF CHIRALITY OF OPTICALLY ACTIVE COMPOUNDS UNIVERSITA DEGLI STUDI DI (IT) 2010-07-01 US disclosed
US-20100144778-A1 Niacin Receptor Agonists, Compositions Containing Such Compounds and Methods of Treatment MERCK SHARP & DOHME LLC 2010-06-10 US disclosed
US-20100144778-A1 Niacin Receptor Agonists, Compositions Containing Such Compounds and Methods of Treatment MERCK SHARP & DOHME LLC 2010-06-10 US disclosed
CN-101612360-A The medicine of treatment hepatitis, liver cirrhosis, hepatocarcinoma JIAHUI XIAO 2009-12-30 CN disclosed
CN-101208082-A Niacin receptor agonists, compositions containing such compounds and methods of treatment MERCK & CO INC (US) 2008-06-25 CN disclosed
WO-2007002557-A1 NIACIN RECEPTOR AGONISTS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT MERCK & CO., INC. (US) 2007-01-04 WO disclosed
US-20060160719-A1 Flavor and fragrance compositions TAKASAGO INTERNATIONAL CORPORATION (JP) 2006-07-20 US disclosed
US-6190685-B1 FOR TREATING IMMUNE DISEASES SUCH AS ACQUIRED IMMUNE DIFICIENCY SYNDROME(AIDS) TAKAHISA KARITA (JP) 2001-02-20 US disclosed
CN-1275914-A Antioxidizing composition for scavenging free radicals, pharmaceutical composition comprising the same, and process for preparing the same KARITA TAKESHI (JP) 2000-12-06 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240285549-A1 CANNABIS OIL COMPOSITIONS AND METHODS FOR PREPARATION THEREOF CNR1, CNR2, PROC PTPN2 4162/4885PTPN1 4090/4885ALDH1A1 1486/4885
US-20060160719-A1 Flavor and fragrance compositions TAS2R8, TAS2R5, TAS2R7 PTPN2 4465/4885PTPN1 3903/4885ALDH1A1 136/4885
US-20100144778-A1 Niacin Receptor Agonists, Compositions Containing Such Compounds and Methods of Treatment HCAR1, HCAR2, GPR119 PTPN2 3619/4885PTPN1 3464/4885ALDH1A1 1145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.