Pulegone

Pulegone

SCHEMBL58181

CC(C)=C1CCC(C)CC1=O

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PTPN2 P17706 1/20 0.35
PTPN1 P18031 1/20 0.35
ALDH1A1 P00352 6/20 0.35
HPGD P15428 4/20 0.35
HTT P42858 1/20 0.35
CRBN Q96SW2 1/20 0.34
KDM4E B2RXH2 2/20 0.34
MAPT P10636 1/20 0.34
ALOX15 P16050 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TLR4 O00206 2/20 0.33
NPC1 O15118 3/20 0.33
RAB9A P51151 3/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
PDK1 Q15118 1/20 0.31
NFE2L2 Q16236 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pulegone SCHEMBL3064832 1.00 PTPN2 (0.35) PTPN2PTPN1ALDH1A1HPGDHTT
Pulegone SCHEMBL38305 1.00 PTPN2 (0.35) PTPN2PTPN1ALDH1A1HPGDHTT
Pulegone SCHEMBL8836781 0.98 ALDH1A1 (0.34) PTPN2PTPN1ALDH1A1HPGDHTT
Pulegone SCHEMBL9292430 0.98 PTPN2 (0.38) PTPN2PTPN1ALDH1A1HPGDHTT
Pulegone SCHEMBL8836768 0.98 ALDH1A1 (0.34) PTPN2PTPN1ALDH1A1HPGDHTT
Pulegone SCHEMBL23752046 0.98 ALDH1A1 (0.34) PTPN2PTPN1ALDH1A1HPGDHTT
Pulegone SCHEMBL8196865 0.88 CYP1A2 (0.36) PTPN1ALDH1A1HPGDKDM4ENPC1
Pulegone SCHEMBL6517913 0.86
Pulegone SCHEMBL17963980 0.82 TLR4 (0.31) TLR4NPC1
Pulegone SCHEMBL17064214 0.82 TLR4 (0.31) TLR4NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8898 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12635710-B2 Methods of using formaldehyde-free antimicrobial compositions in animal by-product compositions EASTMAN CHEMICAL COMPANY (US) 2026-05-26 US claimed
US-20260102358-A1 METHODS FOR MAINTAINING CONCENTRATIONS OF VOLATILE LIPOPHILIC COMPOUNDS IN MANUFACTURE OF COMPOSITIONS AND DOSAGE FORMS CURIO IP LLC (US) 2026-04-16 US claimed
US-12568998-B2 Flavouring composition with balanced taste profile SYMRISE AG (DE) 2026-03-10 US claimed
US-20260027136-A1 CANNABIS BASED THERAPEUTIC AND METHOD OF USE YUZU LV LLC (US) 2026-01-29 US claimed
US-20260014065-A1 PHYTOCHEMICAL INFUSED COSMETIC COMPOSITIONS AND THERAPEUTIC USES THEREOF Dewey Beauty LLC (US) 2026-01-15 US claimed
US-20260007137-A1 FRESHNESS ENHANCING LABELS, SHEETS, AND SACHETS RYP LABS, INC. (US) 2026-01-08 US claimed
US-12514844-B1 Cannabinoid compositions and dosage forms Lock Box LLC (US) 2026-01-06 US claimed
EP-4028059-B1 STABLE MEDICINAL CANNABIDIOL COMPOSITIONS CARDIOL THERAPEUTICS INC (CA) 2025-12-24 EP claimed
US-20250366505-A1 AEROSOL-GENERATING SUBSTRATES AND ENCAPSULATED FLAVORANTS ALTRIA CLIENT SERVICES LLC (US) 2025-12-04 US claimed
US-12439906-B2 Pesticide strip, kit, and methods of use GONZALES JERINA CARMEN (US) 2025-10-14 US claimed
US-4880774-A Sustained release aromatic KURITA WATER INDUSTRIES, LTD. (JP) 1989-11-14 US claimed
US-4861616-A Stable peppermint oil having reduced pulegone content and method of producing the same A. M. TODD COMPANY (US) 1989-08-29 US claimed
EP-0287342-A2 A sustained release aromatic and a process for manufacturing thereof Kurita Water Industries Ltd. (JP) 1988-10-19 EP claimed
US-4766249-A Method of catalytically hydrolyzing alpha, beta-unsaturated carbonyl compounds MALLINCKRODT, INC. (US) 1988-08-23 US claimed
EP-0277688-A2 Method for preparing thiol compounds NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 1988-08-10 EP claimed
EP-0277400-A1 Oral compositions LION CORPORATION (JP) 1988-08-10 EP claimed
CN-87102212-A Method for catalytic hydrolysis of alpha, beta-unsaturated carbonyl compounds 1987-11-04 CN claimed
EP-0242934-A2 Method of catalytically hydrolyzing alpha,beta-unsaturated carbonyl compounds FRIES & FRIES, INC. (US) 1987-10-28 EP claimed
US-4058571-A HYDROGENATION, COBALT-MANGANESE CATALYST BAYER AKTIENGESELLSCHAFT (DT) 1977-11-15 US claimed
US-4052457-A 3,7,11,11-Tetramethyl-spiro-[5,5]undeca-8-ene-1-one TAKASAGO PERFUMERY CO., LTD. (JA) 1977-10-04 US claimed