Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | ABL2 | P42684 | 1/20 | 0.42 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.41 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.41 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4122387 | 0.93 | SLC2A1 (0.54) | MEN1KMT2ASLC2A1GPR119HTT | |
| SCHEMBL4116149 | 0.87 | SLC2A1 (0.53) | MEN1KMT2ASLC2A1GPR119HTT | |
| SCHEMBL4117193 | 0.86 | SLC2A1 (0.50) | MEN1KMT2ASLC2A1GPR119HTT | |
| SCHEMBL4108456 | 0.83 | SLC2A1 (0.49) | MEN1KMT2ASLC2A1GPR119HTT | |
| SCHEMBL4117155 | 0.82 | SLC2A1 (0.48) | MEN1KMT2ASLC2A1GPR119HTT | |
| SCHEMBL4126544 | 0.82 | GPR119 (0.50) | MEN1KMT2ASLC2A1GPR119HDAC1 | |
| SCHEMBL4123371 | 0.82 | SLC2A1 (0.49) | MEN1KMT2ASLC2A1GPR119HTT | |
| SCHEMBL4123730 | 0.82 | GPR119 (0.54) | MEN1KMT2ASLC2A1GPR119HTT | |
| SCHEMBL4123050 | 0.82 | SLC2A1 (0.49) | MEN1KMT2ASLC2A1GPR119HTT | |
| SCHEMBL4109784 | 0.82 | SLC2A1 (0.49) | MEN1KMT2ASLC2A1GPR119HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1494670-A1 | MEDICINE FOR TREATING CANCER | Kowa Co., Ltd. (JP) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003086397-A1 | MEDICINE FOR TREATING CANCER | KOWA CO., LTD. (JP) | 2003-10-23 | — | — | WO | disclosed |