Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | P4HB | P07237 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 4/20 | 0.35 |
| ▸ | TDO2 | P48775 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | FLT1 | P17948 | 1/20 | 0.32 |
| ▸ | FLT4 | P35916 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | ABL2 | P42684 | 1/20 | 0.32 |
| ▸ | CFD | P00746 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5622843 | 0.94 | P4HB (0.48) | KDM4EHPGDALDH1A1LMNAP4HB | |
| SCHEMBL6207810 | 0.89 | KDM4E (0.51) | KDM4EHPGDALDH1A1LMNAP4HB | |
| SCHEMBL6203889 | 0.88 | KDM4E (0.50) | KDM4EHPGDALDH1A1LMNAP4HB | |
| SCHEMBL5623388 | 0.88 | P4HB (0.51) | KDM4EHPGDALDH1A1LMNAP4HB | |
| SCHEMBL31237813 | 0.88 | P4HB (0.51) | KDM4EHPGDALDH1A1LMNAP4HB | |
| SCHEMBL15870201 | 0.88 | P4HB (0.51) | KDM4EHPGDALDH1A1LMNAP4HB | |
| SCHEMBL6207805 | 0.87 | KDM4E (0.48) | KDM4EHPGDALDH1A1LMNAP4HB | |
| SCHEMBL6207800 | 0.87 | KDM4E (0.48) | KDM4EHPGDALDH1A1LMNAP4HB | |
| SCHEMBL30852740 | 0.85 | P4HB (0.51) | KDM4EHPGDALDH1A1LMNAP4HB | |
| SCHEMBL24065517 | 0.85 | P4HB (0.51) | KDM4EHPGDALDH1A1LMNAP4HB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0938474-B1 | CYCLOPROPYLINDOLE COMPOUNDS AND THEIR USE AS PRODRUGS | AUCKLAND UNISERVICES LTD (NZ) | 2005-11-23 | — | — | EP | claimed |