Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9160024 | 0.82 | HSD11B1 (0.44) | ALDH1A1KDM4EHSD11B1HPGDCA1 | |
| SCHEMBL5684191 | 0.78 | HSD11B1 (0.53) | ALDH1A1KDM4EHSD11B1HPGDCA1 | |
| SCHEMBL12208260 | 0.77 | HSD11B1 (0.56) | ALDH1A1KDM4EHSD11B1HPGDCA1 | |
| SCHEMBL1023276 | 0.77 | HSD11B1 (0.60) | ALDH1A1KDM4EHSD11B1HPGDCA1 | |
| SCHEMBL19025570 | 0.77 | HSD11B1 (0.51) | ALDH1A1KDM4EHSD11B1HPGDCA1 | |
| SCHEMBL10785710 | 0.77 | HSD11B1 (0.51) | ALDH1A1KDM4EHSD11B1HPGDCA1 | |
| SCHEMBL30752168 | 0.76 | NPC1 (0.47) | ALDH1A1KDM4EHSD11B1HPGDPOLB | |
| SCHEMBL27579582 | 0.76 | HSD11B1 (0.54) | ALDH1A1KDM4EHSD11B1HPGDCA1 | |
| SCHEMBL2814601 | 0.75 | MAPT (0.55) | ALDH1A1KDM4EHSD11B1CA1CA2 | |
| SCHEMBL27736519 | 0.74 | HSD11B1 (0.61) | ALDH1A1KDM4EHSD11B1HPGDCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1580187-A1 | Apoptogenic and antiproliferative analogs of ceramide | Deigner, Hans-Peter (DE) | 2005-09-28 | — | — | EP | claimed |
| EP-1580187-A1 | Apoptogenic and antiproliferative analogs of ceramide | Deigner, Hans-Peter (DE) | 2005-09-28 | — | — | EP | disclosed |