⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4479231 | 0.92 | — | — | |
| SCHEMBL1797512 | 0.79 | — | — | |
| SCHEMBL12311052 | 0.78 | — | — | |
| SCHEMBL17385977 | 0.74 | — | — | |
| SCHEMBL16469683 | 0.74 | ALDH1A1 (0.37) | — | |
| SCHEMBL1365947 | 0.72 | — | — | |
| SCHEMBL7895514 | 0.72 | THRB (0.44) | — | |
| SCHEMBL1954964 | 0.72 | — | — | |
| SCHEMBL8598989 | 0.72 | THRB (0.44) | — | |
| SCHEMBL1054429 | 0.72 | THRB (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116437913-A | Pharmaceutical compounds for treating complement-mediated disorders | 艾其林医药公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-115362152-A | Compound (I) | 英夫拉索姆有限公司 | 2022-11-18 | — | — | CN | disclosed |
| CN-114375296-A | Nucleic acid polypeptide compositions and uses thereof | 艾维迪提生物科学公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-111491623-A | Compounds and their use in the treatment of cancer | 阿斯利康(瑞典)有限公司 | 2020-08-04 | — | — | CN | disclosed |
| CN-109734747-A | Chiral imino-diacetic phosphate/ester and its derivative | 科勒研究有限公司 | 2019-05-10 | — | — | CN | disclosed |
| CN-103649079-B | Hepatitis c inhibitor and application thereof | ABBVIE 公司 | 2016-11-16 | — | — | CN | disclosed |
| CN-106008272-A | Cationic lipid | 协和发酵麒麟株式会社 | 2016-10-12 | — | — | CN | disclosed |
| CN-104603102-A | Cationic lipid | KYOWA HAKKO KIRIN CO LTD | 2015-05-06 | — | — | CN | disclosed |
| CN-104039759-A | Chiral Imidodiphosphates And Derivatives Thereof | STUDIENGESELLSCHAFT KOHLE MBH | 2014-09-10 | — | — | CN | disclosed |
| CN-103649079-A | Hepatitis C inhibitor and application thereof | ABBVIE INC | 2014-03-19 | — | — | CN | disclosed |
| CN-101370817-B | Cationic oligonucleotides, automated methods of preparing cationic oligonucleotides, and uses thereof | CENTRE NAT RECH SCIENT | 2012-08-08 | — | — | CN | disclosed |
| CN-101370817-A | Cationic oligonucleotides, automated methods of preparing cationic oligonucleotides, and uses thereof | CENTRE NAT RECH SCIENT (FR) | 2009-02-18 | — | — | CN | disclosed |
| CN-101163675-A | Nitrogen-containing heterocyclic compound | KYOWA HAKKO KOGYO KK (JP) | 2008-04-16 | — | — | CN | disclosed |
| CN-101128424-A | Indole compound and use thereof | ONO PHARMACEUTICAL CO (JP) | 2008-02-20 | — | — | CN | disclosed |
| CN-1780821-A | Heterocyclic kinase inhibitors. | ABBOTT LAB (US) | 2006-05-31 | — | — | CN | disclosed |
| EP-1606268-A1 | HETEROCYCLIC KINASE INHIBITORS | Abbott Laboratories (US) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004076424-A1 | HETEROCYCLIC KINASE INHIBITORS | ABBOTT LABORATORIES (US) | 2004-09-10 | — | — | WO | disclosed |