Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.33 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.33 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.33 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.33 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6208492 | 0.84 | ALDH1A1 (0.37) | L3MBTL1POLBKDM4EADORA1GAA | |
| SCHEMBL4849652 | 0.81 | POLB (0.39) | L3MBTL1HDAC6POLBTDP1KDM4E | |
| SCHEMBL6210186 | 0.79 | MAPT (0.32) | TDP1ALDH1A1TSHRMAPT | |
| SCHEMBL20893583 | 0.72 | L3MBTL1 (0.35) | L3MBTL1HDAC6TDP1ADORA2AGAA | |
| SCHEMBL20893570 | 0.72 | KDM4E (0.36) | KDM4EADORA2AADORA1TUBB4ATUBB | |
| SCHEMBL4855010 | 0.71 | TARBP2 (0.42) | L3MBTL1POLBKDM4EGAAALDH1A1 | |
| SCHEMBL20893577 | 0.71 | L3MBTL1 (0.34) | L3MBTL1HDAC6TDP1ADORA2AGAA | |
| SCHEMBL6209061 | 0.70 | L3MBTL1 (0.35) | L3MBTL1HDAC6POLBTDP1KDM4E | |
| SCHEMBL4854555 | 0.69 | ALDH1A1 (0.36) | KDM4EGAAALDH1A1LMNATSHR | |
| SCHEMBL4857338 | 0.68 | NPSR1 (0.41) | KDM4EGAAALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1440075-B1 | NOVEL 3BETA-AMINO AZABICYCLOOCTANE HETEROAROMATIC AMIDE DERIVATIVES, PREPARATION METHOD AND THERAPEUTIC USES THEREOF | PF MEDICAMENT (FR) | 2005-06-08 | — | — | EP | claimed |