Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 10/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 8/20 | 0.47 |
| ▸ | MAPK9 | P45984 | 8/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 8/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6284192 | 0.81 | PTK2 (0.49) | — | |
| SCHEMBL5441554 | 0.76 | PIK3CA (0.71) | PIK3CAMAPK8MAPK9MAPK10MAPK1 | |
| SCHEMBL5170655 | 0.75 | CDK2 (0.50) | — | |
| SCHEMBL3637688 | 0.74 | PIK3CA (0.69) | PIK3CAMAPK8MAPK9MAPK10MAPK1 | |
| SCHEMBL14559576 | 0.73 | MAPK1 (0.62) | PIK3CAMAPK8MAPK9MAPK10MAPK1 | |
| SCHEMBL15921102 | 0.73 | GRM5 (0.50) | — | |
| SCHEMBL1041933 | 0.73 | CDK2 (0.41) | — | |
| SCHEMBL6420701 | 0.72 | ABL1 (0.42) | PIK3CAMAPK8MAPK9MAPK10MAPK1 | |
| SCHEMBL18274603 | 0.72 | CSF1R (0.43) | — | |
| SCHEMBL14518147 | 0.71 | ATR (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050267126-A1 | Compounds derived from aryl carbamates, preparation thereof and uses of same | CEREP (FR) | 2005-12-01 | — | — | US | disclosed |
| EP-1530564-A2 | COMPOUNDS DERIVED FROM ARYL CARBAMATES, PREPARATION THEREOF AND USES OF SAME | Cerep (FR) | 2005-05-18 | — | — | EP | disclosed |
| WO-2004018436-A2 | COMPOUNDS DERIVED FROM ARYL CARBAMATES, PREPARATION THEREOF AND USES OF SAME | CEREP (FR) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050267126-A1 | Compounds derived from aryl carbamates, preparation thereof and uses of same | HTR4, HTR2B, HTR1B | PIK3CA 2770/4885MAPK8 4009/4885MAPK9 3701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.