Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 3/20 | 0.42 |
| ▸ | SIK1 | P57059 | 3/20 | 0.42 |
| ▸ | SIK2 | Q9H0K1 | 3/20 | 0.42 |
| ▸ | SIK3 | Q9Y2K2 | 3/20 | 0.42 |
| ▸ | FLT3 | P36888 | 3/20 | 0.39 |
| ▸ | AURKA | O14965 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6415598 | 0.76 | KDM4E (0.46) | KDM4EALDH1A1LMNA | |
| SCHEMBL12813911 | 0.72 | HTR2A (0.57) | KDM4EALDH1A1HTR1ADRD2HTR2A | |
| SCHEMBL6208080 | 0.72 | PIK3CA (0.47) | PIK3CAMAPK1MAPK8MAPK9MAPK10 | |
| SCHEMBL5447527 | 0.69 | PIK3CA (0.61) | PIK3CAMAPK1MAPK8MAPK9MAPK10 | |
| SCHEMBL4341121 | 0.69 | PIK3CA (0.57) | PIK3CAMAPK1MAPK8MAPK9MAPK10 | |
| SCHEMBL10672091 | 0.66 | HTR2A (0.53) | KDM4EALDH1A1HTR1ADRD2HTR2A | |
| SCHEMBL14506589 | 0.66 | MAPK1 (0.59) | PIK3CAMAPK1MAPK8MAPK9MAPK10 | |
| SCHEMBL4353813 | 0.66 | PIK3CA (0.53) | PIK3CAMAPK1MAPK8MAPK9MAPK10 | |
| SCHEMBL24993525 | 0.65 | DRD2 (0.40) | KDM4EALDH1A1DRD2SIGMAR1 | |
| SCHEMBL24993370 | 0.65 | PTPN11 (0.44) | MAPK1ALDH1A1DRD2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050267126-A1 | Compounds derived from aryl carbamates, preparation thereof and uses of same | CEREP (FR) | 2005-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050267126-A1 | Compounds derived from aryl carbamates, preparation thereof and uses of same | HTR4, HTR2B, HTR1B | ABL1 1146/4885SIK1 4639/4885SIK2 4474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.