Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 8/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6209136 | 0.89 | RAB9A (0.42) | RAB9ASMN1; SMN2NPC1MAPTLMNA | |
| SCHEMBL13314812 | 0.83 | RAB9A (0.47) | RAB9ASMN1; SMN2NPC1MAPTLMNA | |
| SCHEMBL3538338 | 0.83 | RAB9A (0.47) | RAB9ASMN1; SMN2NPC1MAPTLMNA | |
| SCHEMBL6208744 | 0.80 | RAB9A (0.46) | RAB9ASMN1; SMN2NPC1MAPTLMNA | |
| Formic Acid SCHEMBL3603162 | 0.80 | RAB9A (0.44) | RAB9ASMN1; SMN2NPC1MAPTLMNA | |
| SCHEMBL6210026 | 0.79 | RAB9A (0.44) | RAB9ASMN1; SMN2NPC1MAPTLMNA | |
| SCHEMBL6208826 | 0.79 | TSHR (0.34) | RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL6210542 | 0.77 | MAPT (0.46) | RAB9ASMN1; SMN2NPC1MAPTLMNA | |
| SCHEMBL13314888 | 0.74 | RAB9A (0.48) | RAB9ASMN1; SMN2NPC1MAPTLMNA | |
| SCHEMBL3536924 | 0.73 | RAB9A (0.46) | RAB9ASMN1; SMN2NPC1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1608662-A1 | GUANIDINE DERIVATIVES AND USE THEREOF AS NEUROPEPTIDE FF RECEPTOR ANTAGONISTS | Actelion Pharmaceuticals Ltd. (CH) | 2005-12-28 | — | — | EP | claimed |
| WO-2004083218-A1 | GUANIDINE DERIVATIVES AND USE THEREOF AS NEUROPEPTIDE FF RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2004-09-30 | — | — | WO | claimed |
| EP-1608662-A1 | GUANIDINE DERIVATIVES AND USE THEREOF AS NEUROPEPTIDE FF RECEPTOR ANTAGONISTS | Actelion Pharmaceuticals Ltd. (CH) | 2005-12-28 | — | — | EP | disclosed |
| WO-2004083218-A1 | GUANIDINE DERIVATIVES AND USE THEREOF AS NEUROPEPTIDE FF RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2004-09-30 | — | — | WO | disclosed |