Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC8 | Q09428 | 12/20 | 0.38 |
| ▸ | KCNJ11 | Q14654 | 12/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 4/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 4/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6792625 | 0.71 | ABCC8 (0.44) | ABCC8KCNJ11GRIA1GRIA2GRIA3 | |
| SCHEMBL3870329 | 0.71 | GRIA1 (0.46) | ABCC8KCNJ11GRIA1GRIA2GRIA3 | |
| SCHEMBL6798761 | 0.69 | ABCC8 (0.43) | ABCC8KCNJ11GRIA1GRIA2GRIA3 | |
| SCHEMBL6997132 | 0.69 | ABCC8 (0.43) | ABCC8KCNJ11GRIA1GRIA2GRIA3 | |
| SCHEMBL8286612 | 0.69 | ABCC8 (0.50) | ABCC8KCNJ11GRIA1GRIA2GRIA3 | |
| SCHEMBL4260154 | 0.66 | ABCC8 (0.46) | ABCC8KCNJ11GRIA1GRIA2GRIA3 | |
| SCHEMBL7565061 | 0.66 | ABCC8 (0.43) | ABCC8KCNJ11GRIA1GRIA2GRIA3 | |
| SCHEMBL4261624 | 0.63 | ABCC8 (0.45) | ABCC8KCNJ11GRIA1GRIA2GRIA3 | |
| SCHEMBL2344068 | 0.63 | ABCC8 (0.45) | ABCC8KCNJ11GRIA1GRIA2GRIA3 | |
| SCHEMBL4264221 | 0.63 | ABCC8 (0.45) | ABCC8KCNJ11GRIA1GRIA2GRIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214325-B1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPases) | NOVO NORDISK AS (DK) | 2005-11-09 | — | — | EP | claimed |