Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA6 | Q9UK32 | 2/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.32 |
| ▸ | RPS6KA3 | P51812 | 3/20 | 0.32 |
| ▸ | GALR1 | P47211 | 1/20 | 0.32 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | GRK6 | P43250 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | IDH2 | P48735 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5553533 | 0.91 | RAB9A (0.39) | RPS6KA6S1PR1IDH2RAB9A | |
| SCHEMBL6209675 | 0.90 | CTSS (0.31) | SOS1GRK6HIF1AHSD17B10RAB9A | |
| SCHEMBL4829579 | 0.86 | GALR1 (0.41) | RPS6KA6SOS1TNK2CDK1CDK4 | |
| SCHEMBL5029060 | 0.82 | RAB9A (0.41) | SOS1IDH2RAB9A | |
| SCHEMBL5553440 | 0.81 | CTSS (0.40) | RAB9A | |
| SCHEMBL4838488 | 0.81 | RAB9A (0.39) | IDH2RAB9A | |
| SCHEMBL5553518 | 0.81 | RAB9A (0.37) | CDK1RAB9A | |
| SCHEMBL5553462 | 0.81 | IDH2 (0.41) | GALR1IDH2RAB9A | |
| SCHEMBL5553403 | 0.80 | GALR1 (0.38) | GALR1IDH2RAB9A | |
| SCHEMBL4832646 | 0.80 | GALR1 (0.44) | GALR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560817-A1 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | Reddy US Therapeutics, Inc. (US) | 2005-08-10 | — | — | EP | claimed |
| WO-2004026844-A1 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | REDDY US THERAPEUTICS, INC. (US) | 2004-04-01 | — | — | WO | claimed |