Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 15/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.36 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4041438 | 0.90 | CTSK (0.56) | CTSKCTSSADRB2ADRB1ADRB3 | |
| SCHEMBL6214663 | 0.89 | CTSK (0.51) | CTSKCTSSSMYD3 | |
| SCHEMBL4042258 | 0.88 | CTSK (0.51) | CTSKCTSSADRB2ADRB1ADRB3 | |
| SCHEMBL4046529 | 0.87 | CTSK (0.49) | CTSKCTSSADRB2ADRB1ADRB3 | |
| SCHEMBL6209624 | 0.87 | CTSK (0.59) | CTSKCTSSITGB3ITGA2BITGA2 | |
| SCHEMBL4045775 | 0.86 | CTSK (0.49) | CTSKCTSSADRB2ADRB1ADRB3 | |
| SCHEMBL4044861 | 0.86 | CTSK (0.49) | CTSKCTSSADRB2ADRB1ADRB3 | |
| SCHEMBL6210948 | 0.84 | CTSK (0.48) | CTSKCTSS | |
| SCHEMBL4041465 | 0.83 | CTSK (0.51) | CTSKCTSS | |
| SCHEMBL4045440 | 0.83 | CTSK (0.59) | CTSKCTSSADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |