Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 15/20 | 0.59 |
| ▸ | CTSS | P25774 | 3/20 | 0.46 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 2/20 | 0.35 |
| ▸ | CTSB | P07858 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6211024 | 0.93 | CTSK (0.60) | CTSKCTSS | |
| SCHEMBL4044020 | 0.88 | CTSK (0.75) | CTSKCTSSITGB3ITGA2BCDK4 | |
| SCHEMBL5941816 | 0.88 | CTSK (0.75) | CTSKCTSSITGB3ITGA2BCDK4 | |
| SCHEMBL4368915 | 0.88 | CTSK (0.75) | CTSKCTSSITGB3ITGA2BCDK4 | |
| SCHEMBL6209777 | 0.88 | CTSK (0.63) | CTSKCTSSSMYD3 | |
| SCHEMBL4368912 | 0.88 | CTSK (0.75) | CTSKCTSSITGB3ITGA2BCDK4 | |
| SCHEMBL4040434 | 0.87 | CTSK (0.64) | CTSKCTSSCDK4CCNA2CCND1 | |
| SCHEMBL6208729 | 0.87 | CTSK (0.49) | CTSKCTSSSMYD3ITGB3ITGA2B | |
| SCHEMBL4038951 | 0.86 | CTSK (0.57) | CTSKCTSSITGB3ITGA2BCDK4 | |
| SCHEMBL4038247 | 0.86 | CTSK (0.59) | CTSKCTSSSMYD3ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |