SCHEMBL6208741

SCHEMBL6208741

Fc1cc(F)c(-c2c(Cl)nc3nc(C=S)nn3c2Cl)c(F)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6480083 0.83
SCHEMBL6479391 0.79
SCHEMBL5955395 0.78 GRM5 (0.34)
SCHEMBL5227759 0.77 DHODH (0.38)
SCHEMBL5745486 0.76 KDM4E (0.36)
SCHEMBL3276173 0.71 ALDH1A1 (0.39)
SCHEMBL6068158 0.69 ALDH1A1 (0.36)
SCHEMBL6206302 0.69 ABCB1 (0.48)
SCHEMBL5955543 0.66 HPGD (0.34)
SCHEMBL5232625 0.66 CDK2 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050272748-A1 2-Mercapto-substituted triazolopyrimidines, methods for the production thereof, the use of the same for controlling patogenic fungi, and agents containing said compounds BASF AKTIENGESELLSCHAFT (DE) 2005-12-08 US disclosed
EP-1575957-A1 2-MERCAPTO-SUBSTITUTED TRIAZOLOPYRIMIDINES, METHODS FOR THE PRODUCTION THEREOF, THE USE OF THE SAME FOR CONTROLLING PATHOGENIC FUNGI, AND AGENTS CONTAINING SAID COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2005-09-21 EP disclosed
WO-2004046149-A1 2-MERCAPTO-SUBSTITUTED TRIAZOLOPYRIMIDINES, METHODS FOR THE PRODUCTION THEREOF, THE USE OF THE SAME FOR CONTROLLING PATHOGENIC FUNGI, AND AGENTS CONTAINING SAID COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2004-06-03 WO disclosed