Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23944468 | 0.88 | KDM4E (0.43) | ALDH1A1KMT2ATSHRPOLBMAPK1 | |
| SCHEMBL23925483 | 0.88 | ALDH1A1 (0.38) | ALDH1A1KMT2ATSHRPOLBMAPK1 | |
| SCHEMBL5096454 | 0.87 | ALDH1A1 (0.46) | ALDH1A1KMT2ATSHRPOLBMAPK1 | |
| SCHEMBL3426566 | 0.86 | ALDH1A1 (0.36) | ALDH1A1KMT2ATSHRPOLBMAPK1 | |
| SCHEMBL6530592 | 0.85 | MBOAT4 (0.43) | ALDH1A1KMT2ATSHRPOLBMAPK1 | |
| SCHEMBL5433238 | 0.85 | ALDH1A1 (0.45) | ALDH1A1KMT2ATSHRPOLBMAPK1 | |
| SCHEMBL5622818 | 0.85 | ALDH1A1 (0.39) | ALDH1A1KMT2ATSHRPOLBMEN1 | |
| SCHEMBL6068161 | 0.85 | ALDH1A1 (0.38) | ALDH1A1KMT2ATSHRPOLBMAPK1 | |
| SCHEMBL6189796 | 0.85 | SMN1; SMN2 (0.41) | ALDH1A1KMT2ATSHRPOLBMAPK1 | |
| SCHEMBL23925484 | 0.85 | EGLN2 (0.48) | ALDH1A1KMT2ATSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4653442-A1 | POLYCYCLIC COMPOUND FOR TREATING NEUROLOGICAL DISEASES AND TUMORS | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024153202-A1 | POLYCYCLIC COMPOUND FOR TREATING NEUROLOGICAL DISEASES AND TUMORS | 中国科学院上海有机化学研究所 | 2024-07-25 | — | — | WO | disclosed |
| CN-118359616-A | Polycyclic compounds as therapeutic agents for neurological diseases and tumors | 中国科学院上海有机化学研究所 | 2024-07-19 | — | — | CN | disclosed |
| US-20230167121-A1 | SUBSTITUTED {1,2,4,} TRIAZOLO{1,5-A} PYRIMIDINE COMPOUNDS AND USE IN STABILIZING MICROTUBULES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-06-01 | — | — | US | disclosed |
| US-11623927-B2 | Substituted [1,2,4]triazolo[1,5-a]pyrimidines for stabilizing microtubules | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2023-04-11 | — | — | US | disclosed |
| US-11623927-B2 | Substituted [1,2,4]triazolo[1,5-a]pyrimidines for stabilizing microtubules | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2023-04-11 | — | — | US | disclosed |
| EP-4136089-A1 | SUBSTITUTED {1,2,4,} TRIAZOLO{1,5-A} PYRIMIDINE COMPOUNDS AND USE IN STABILIZING MICROTUBULES | The Trustees of The University of Pennsylvania (US) | 2023-02-22 | — | — | EP | disclosed |
| CN-115397826-A | Substituted {1,2,4, } triazolo {1,5-a } pyrimidine compounds and their use for the stabilization of microtubules | 宾夕法尼亚大学理事会 | 2022-11-25 | — | — | CN | disclosed |
| US-20220227772-A1 | DEUTERATED TRIAZOLOPYRIMIDINES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-07-21 | — | — | US | disclosed |
| WO-2021211408-A1 | SUBSTITUTED {1,2,4,} TRIAZOLO{1,5-A} PYRIMIDINE COMPOUNDS AND USE IN STABILIZING MICROTUBULES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2021-10-21 | — | — | WO | disclosed |
| US-20050090508-A1 | 6-[(Substituted)phenyl]triazolopyrimidines as anticancer agents | WYETH HOLDINGS CORPORATION (US) | 2005-04-28 | — | — | US | disclosed |
| WO-2005030775-A1 | 6-[(SUBSTITUTED)PHENYL]TRIAZOLOPYRIMIDINES AS ANTICANCER AGENTS | WYETH HOLDINGS CORPORATION (US) | 2005-04-07 | — | — | WO | disclosed |
| WO-2005030216-A1 | 5-ARYLPYRIMIDINES AS ANTICANCER AGENTS | WYETH HOLDINGS CORPORATION (US) | 2005-04-07 | — | — | WO | disclosed |
| US-20050075357-A1 | 5-arylpyrimidines as anticancer agents | WYETH (US) | 2005-04-07 | — | — | US | disclosed |
| US-6855718-B2 | 7-(r)-aminotriazolopyrimidines, the production thereof and use of the same for combatting phytopathogenic fungi | BASF AKTIENGESELLSCHAFT (DE) | 2005-02-15 | — | — | US | disclosed |
| US-20040176398-A1 | Triazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2004-09-09 | — | — | US | disclosed |
| US-20040110771-A1 | 7-(r)-aminotriazolopyrimidines, the production thereof and use of the same for combatting phytopathogenic fungi | BASF AKTIENGESELLSCHAFT (DE) | 2004-06-10 | — | — | US | disclosed |
| US-6297251-B1 | Fungicidal trifluorophenyl-triazolopyrimidines | AMERICAN CYANAMID CO. | 2001-10-02 | — | — | US | disclosed |
| EP-0975634-B1 | FUNGICIDAL TRIFLUOROPHENYL-TRIAZOLOPYRIMIDINES | BASF AG (DE) | 2001-07-04 | — | — | EP | disclosed |
| US-6117876-A | Fungicidal trifluorophenyl-triazolopyrimidines | AMERICAN CYANAMID COMPANY (US) | 2000-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220227772-A1 | DEUTERATED TRIAZOLOPYRIMIDINES | MAPT, TUBB6, MAP2 | ALDH1A1 2231/4885KMT2A 2175/4885TSHR 1749/4885 |
| US-11623927-B2 | Substituted [1,2,4]triazolo[1,5-a]pyrimidines for stabilizing microtubules | TUBB1, TUBA1B, TUBA1C | ALDH1A1 3710/4885KMT2A 1936/4885TSHR 880/4885 |
| US-20040110771-A1 | 7-(r)-aminotriazolopyrimidines, the production thereof and use of the same for combatting phytopathogenic fungi | CBR1, CBR3, DPM1 | ALDH1A1 1806/4885KMT2A 856/4885TSHR 4254/4885 |
| US-20230167121-A1 | SUBSTITUTED {1,2,4,} TRIAZOLO{1,5-A} PYRIMIDINE COMPOUNDS AND USE IN STABILIZING MICROTUBULES | MAPT, TUBA4A, MAP4 | ALDH1A1 2113/4885KMT2A 2234/4885TSHR 4078/4885 |
| US-20040176398-A1 | Triazolopyrimidines | Q6ZSR9, UMPS, UPP1 | ALDH1A1 236/4885KMT2A 1946/4885TSHR 2132/4885 |
| US-20050075357-A1 | 5-arylpyrimidines as anticancer agents | DPYD, ABCC1, ARF5 | ALDH1A1 430/4885KMT2A 2162/4885TSHR 4085/4885 |
| US-20050090508-A1 | 6-[(Substituted)phenyl]triazolopyrimidines as anticancer agents | ABCC1, ABCB1, TUBB6 | ALDH1A1 1838/4885KMT2A 3055/4885TSHR 3624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.