Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3572773 | 0.87 | MEN1 (0.36) | MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL3582645 | 0.85 | MEN1 (0.35) | MEN1KMT2AALDH1A1 | |
| SCHEMBL6208769 | 0.74 | LMNA (0.37) | MEN1KMT2AALDH1A1 | |
| SCHEMBL19744030 | 0.73 | MAPT (0.35) | MEN1KMT2A | |
| SCHEMBL30934837 | 0.73 | MAPT (0.35) | MEN1KMT2A | |
| SCHEMBL4693682 | 0.72 | MEN1 (0.35) | MEN1KMT2A | |
| SCHEMBL6209298 | 0.71 | MAPT (0.33) | ALDH1A1 | |
| SCHEMBL3972170 | 0.70 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1 | |
| SCHEMBL27755208 | 0.70 | POLB (0.42) | MEN1KMT2AALDH1A1 | |
| SCHEMBL23094542 | 0.68 | KMT2A (0.43) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560829-A1 | PYRIMIDO COMPOUNDS HAVING ANTIPROLIFERATIVE ACTIVITY (II) | F. HOFFMANN-LA ROCHE AG (CH) | 2005-08-10 | — | — | EP | disclosed |
| WO-2004041821-A1 | PYRIMIDO COMPOUNDS HAVING ANTIPROLIFERATIVE ACTIVITY (II) | F. HOFFMANN-LA ROCHE AG (CH) | 2004-05-21 | — | — | WO | disclosed |