Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.57 |
| ▸ | NPC1 | O15118 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.47 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13925101 | 0.88 | RAB9A (0.63) | RAB9ANPC1SMN1; SMN2TP53MAPT | |
| SCHEMBL11413702 | 0.86 | SMN1; SMN2 (0.64) | RAB9ANPC1SMN1; SMN2TP53MAPT | |
| SCHEMBL4243274 | 0.84 | RAB9A (0.69) | RAB9ANPC1SMN1; SMN2TP53MAPT | |
| SCHEMBL19880499 | 0.83 | RAB9A (0.65) | RAB9ANPC1SMN1; SMN2TP53MAPT | |
| Hydrochloric Acid SCHEMBL3801257 | 0.82 | RAB9A (0.67) | RAB9ANPC1SMN1; SMN2TP53MAPT | |
| SCHEMBL10758900 | 0.82 | KMT2A (0.64) | RAB9ANPC1SMN1; SMN2POLBCA12 | |
| SCHEMBL11593321 | 0.80 | SMN1; SMN2 (0.67) | RAB9ANPC1SMN1; SMN2TP53MAPT | |
| SCHEMBL19779915 | 0.79 | NOX1 (0.58) | RAB9ANPC1SMN1; SMN2TP53MAPT | |
| SCHEMBL22096914 | 0.79 | SMN1; SMN2 (0.62) | RAB9ANPC1SMN1; SMN2TP53MAPT | |
| SCHEMBL19779914 | 0.79 | RAB9A (0.73) | RAB9ANPC1SMN1; SMN2TP53CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599167-A2 | NOVEL BENZIMIDAZOLE AND IMIDAZOPYRIDINE DERIVATIVES AND USE THEREOF AS A MEDICAMENT | Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.) (FR) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004075823-A2 | NOVEL BENZIMIDAZOLE AND IMIDAZOPYRIDINE DERIVATIVES AND USE THEREOF AS A MEDICAMENT | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2004-09-10 | — | — | WO | disclosed |