Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.69 |
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.47 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3801257 | 0.98 | RAB9A (0.67) | RAB9AMAPTSMN1; SMN2NPC1CA12 | |
| SCHEMBL11895730 | 0.85 | RAB9A (0.81) | RAB9AMAPTSMN1; SMN2NPC1CA12 | |
| SCHEMBL13925101 | 0.84 | RAB9A (0.63) | RAB9AMAPTSMN1; SMN2NPC1TDP1 | |
| SCHEMBL6208837 | 0.84 | RAB9A (0.57) | RAB9AMAPTSMN1; SMN2NPC1CA12 | |
| SCHEMBL19779914 | 0.83 | RAB9A (0.73) | RAB9ASMN1; SMN2NPC1CA12CA1 | |
| SCHEMBL8772924 | 0.83 | RAB9A (1.00) | RAB9AMAPTSMN1; SMN2NPC1CA12 | |
| SCHEMBL10758900 | 0.82 | KMT2A (0.64) | RAB9ASMN1; SMN2NPC1CA12CA1 | |
| SCHEMBL11413702 | 0.82 | SMN1; SMN2 (0.64) | RAB9AMAPTSMN1; SMN2NPC1KMT2A | |
| SCHEMBL22096914 | 0.79 | SMN1; SMN2 (0.62) | RAB9AMAPTSMN1; SMN2NPC1KMT2A | |
| SCHEMBL19779915 | 0.79 | NOX1 (0.58) | RAB9AMAPTSMN1; SMN2NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615925-B1 | IMIDAZOPYRIDINE DERIVATIVES AS MELANOCORTIN RECEPTOR AGONISTS | IPSEN PHARMA (FR) | 2009-05-27 | — | — | EP | disclosed |
| EP-1599167-B1 | BENZIMIDAZOLE AND IMIDAZOPYRIDINE DERIVATIVES HAVING AFFINITY FOR THE MELANOCORTIN RECEPTORS AND USE THEREOF AS A MEDICAMENT | SOD CONSEILS RECH APPLIC (FR) | 2007-10-03 | — | — | EP | disclosed |