Sugi Predict

Sugi Predict / Compounds / SCHEMBL6208926

SCHEMBL6208926

SCHEMBL6208926

CSc1sc(C(=N)NC(=O)OC(C)(C)C)cc1S(=O)(=O)c1cccc(-c2cccc(C=O)c2)c1C

nearest known ligand 0.51

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ C1S P09871 20/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6210648 0.86 C1S (0.41) C1S
SCHEMBL5840040 0.85 C1S (0.53) C1S
SCHEMBL5840270 0.85 C1S (0.59) C1S
SCHEMBL5839752 0.84 C1S (0.56) C1S
SCHEMBL6209981 0.82 C1S (0.50) C1S
SCHEMBL6208923 0.82 C1S (0.42) C1S
SCHEMBL6208918 0.82 C1S (0.42) C1S
SCHEMBL5840810 0.78 C1S (0.50) C1S
SCHEMBL5840684 0.78 C1S (0.57) C1S
SCHEMBL8360973 0.77 C1S (0.56) C1S

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1549632-A4 NOVEL THIOPHENE AMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATING COMPLEMENT-MEDIATED DISEASES AND CONDITIONS DIMENSIONAL PHARM INC (US) 2005-11-09 — — EP disclosed
EP-1549632-A1 NOVEL THIOPHENE AMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATING COMPLEMENT-MEDIATED DISEASES AND CONDITIONS 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 2005-07-06 — — EP disclosed
WO-2003099805-A1 NOVEL THIOPHENE AMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATING COMPLEMENT-MEDIATED DISEASES AND CONDITIONS 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 2003-12-04 — — WO disclosed