Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.61 |
| ▸ | NPC1 | O15118 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | MITF | O75030 | 1/20 | 0.58 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.57 |
| ▸ | CASR | P41180 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6208226 | 0.85 | KMT2A (0.56) | USP2KMT2ARAB9ANPC1MEN1 | |
| SCHEMBL27487690 | 0.83 | USP2 (1.00) | USP2KMT2ARAB9ANPC1MEN1 | |
| SCHEMBL14442613 | 0.81 | TP53 (0.84) | USP2KMT2ARAB9ANPC1MEN1 | |
| SCHEMBL8176742 | 0.81 | SMN1; SMN2 (0.81) | USP2KMT2ARAB9ANPC1MEN1 | |
| SCHEMBL31040569 | 0.80 | TP53 (0.87) | USP2KMT2ARAB9ANPC1MEN1 | |
| SCHEMBL4893387 | 0.80 | TP53 (0.87) | USP2KMT2ARAB9ANPC1MEN1 | |
| SCHEMBL8686054 | 0.78 | SLC7A5 (0.59) | USP2KMT2ARAB9ANPC1MEN1 | |
| SCHEMBL17084260 | 0.78 | TP53 (0.84) | USP2KMT2ARAB9ANPC1MEN1 | |
| Oxirane SCHEMBL29014918 | 0.78 | USP2 (0.87) | USP2KMT2ARAB9ANPC1MEN1 | |
| SCHEMBL29200389 | 0.78 | TP53 (0.68) | USP2KMT2ARAB9ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189612-A4 | VLA-4 INHIBITOR COMPOUNDS | DAIICHI SEIYAKU CO (JP) | 2005-02-16 | — | — | EP | disclosed |
| EP-1189612-A1 | VLA-4 INHIBITOR COMPOUNDS | Daiichi Pharmaceutical Co., Ltd. (JP) | 2002-03-27 | — | — | EP | disclosed |
| WO-2001000206-A1 | VLA-4 INHIBITOR COMPOUNDS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-01-04 | — | — | WO | disclosed |