Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.78 |
| ▸ | MEN1 | O00255 | 5/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.76 |
| ▸ | RAB9A | P51151 | 4/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | NPC1 | O15118 | 3/20 | 0.70 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxirane SCHEMBL29014918 | 0.93 | USP2 (0.87) | USP2L3MBTL1MEN1KMT2ARAB9A | |
| SCHEMBL5103284 | 0.91 | USP2 (0.84) | USP2L3MBTL1MEN1KMT2ARAB9A | |
| SCHEMBL8704595 | 0.90 | USP2 (0.81) | USP2L3MBTL1MEN1KMT2ARAB9A | |
| SCHEMBL8705939 | 0.89 | USP2 (0.80) | USP2L3MBTL1MEN1KMT2ARAB9A | |
| SCHEMBL6171858 | 0.88 | L3MBTL1 (1.00) | USP2L3MBTL1MEN1KMT2ARAB9A | |
| SCHEMBL30452440 | 0.86 | RAB9A (1.00) | USP2L3MBTL1MEN1KMT2ARAB9A | |
| SCHEMBL5142657 | 0.84 | NPC1 (0.75) | USP2L3MBTL1MEN1KMT2ARAB9A | |
| SCHEMBL11900270 | 0.84 | EPHX2 (0.81) | USP2L3MBTL1MEN1KMT2ARAB9A | |
| SCHEMBL3645379 | 0.84 | USP2 (0.72) | USP2L3MBTL1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6209008 | 0.83 | USP2 (0.71) | USP2L3MBTL1MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114539129-B | Allylamine bifunctional compound and application thereof | 上海中医药大学附属龙华医院 | 2023-06-09 | — | — | CN | disclosed |
| WO-2022259219-A1 | NOVEL MELATONERGIC LIGANDS AND USES THEREOF | GOBBI GABRIELLA (CA) | 2022-12-15 | — | — | WO | disclosed |
| CN-114539129-A | Allylamine bifunctional compound and application thereof | 上海中医药大学附属龙华医院 | 2022-05-27 | — | — | CN | disclosed |
| CN-102153433-B | N-monosubstituted-alpha-carbonylamide compound and preparation method thereof | UNIV SHANGHAI | 2013-09-04 | — | — | CN | disclosed |
| CN-102153433-A | N-monosubstituted-alpha-carbonylamide compound and preparation method thereof | UNIV SHANGHAI | 2011-08-17 | — | — | CN | disclosed |
| CN-1195740-C | Pharmaceutical composition containing 2-quinolinone | LAFON LABOR (FR) | 2005-04-06 | — | — | CN | disclosed |
| CN-1309639-A | Pharmaceutical composition containing 2-quinolinone | LAFON LABOR (FR) | 2001-08-22 | — | — | CN | disclosed |