Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 13/20 | 0.57 |
| ▸ | KIF23 | Q02241 | 1/20 | 0.42 |
| ▸ | KLK1 | P06870 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3961772 | 0.92 | KIF11 (0.67) | KIF11KIF23 | |
| SCHEMBL6206668 | 0.91 | KIF11 (0.59) | KIF11KIF23 | |
| SCHEMBL6207965 | 0.88 | KIF11 (0.56) | KIF11KIF23 | |
| SCHEMBL6209290 | 0.83 | KIF11 (0.52) | KIF11KIF23 | |
| SCHEMBL5739696 | 0.83 | KIF11 (0.55) | KIF11KIF23TSHR | |
| SCHEMBL4859195 | 0.81 | KIF11 (0.54) | KIF11KIF23 | |
| SCHEMBL4038794 | 0.81 | KIF11 (0.86) | KIF11 | |
| SCHEMBL3962257 | 0.81 | KIF11 (0.65) | KIF11KIF23 | |
| Hydrochloric Acid SCHEMBL4039994 | 0.81 | KIF11 (0.85) | KIF11 | |
| SCHEMBL3905973 | 0.80 | KIF11 (0.51) | KIF11KIF23 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1601673-A1 | NOVEL FUSED HETEROCYCLES AND USES THEREOF | AstraZeneca AB (SE) | 2005-12-07 | — | — | EP | disclosed |
| WO-2004078758-A1 | NOVEL FUSED HETEROCYCLES AND USES THEREOF | ASTRAZENECA AB (SE) | 2004-09-16 | — | — | WO | disclosed |