Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | USP2 | O75604 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SLC27A1 | Q6PCB7 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4197541 | 0.78 | ALDH1A1 (0.78) | ALDH1A1MAPK1KMT2AUSP2TSHR | |
| SCHEMBL6213422 | 0.78 | BCHE (0.45) | ALDH1A1MAPK1KMT2AUSP2TSHR | |
| SCHEMBL18389044 | 0.74 | ALDH1A1 (1.00) | ALDH1A1MAPK1KMT2AUSP2TSHR | |
| SCHEMBL4215730 | 0.74 | ALDH1A1 (0.71) | ALDH1A1MAPK1KMT2AUSP2TSHR | |
| SCHEMBL4215906 | 0.71 | ALDH1A1 (1.00) | ALDH1A1MAPK1USP2TSHRPKM | |
| SCHEMBL6412028 | 0.70 | GAA (0.80) | ALDH1A1MAPK1KMT2AUSP2TSHR | |
| SCHEMBL11888617 | 0.70 | LMNA (0.67) | ALDH1A1MAPK1NPSR1HTTLMNA | |
| SCHEMBL15983692 | 0.70 | ALDH1A1 (1.00) | ALDH1A1KMT2AUSP2TSHRMEN1 | |
| SCHEMBL18559233 | 0.70 | MAPT (1.00) | ALDH1A1MAPK1USP2TSHRMAPT | |
| SCHEMBL6405002 | 0.68 | ALDH1A1 (0.64) | ALDH1A1KMT2AUSP2TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1553179-A1 | MOUSE-ORIGIN PROTEINS FORMING DOMAIN OR USE THEREOF | Riken (JP) | 2005-07-13 | — | — | EP | disclosed |