Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.42 |
| ▸ | CTSS | P25774 | 5/20 | 0.35 |
| ▸ | CTSV | O60911 | 2/20 | 0.35 |
| ▸ | CTSL | P07711 | 2/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | MMP9 | P14780 | 2/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6212349 | 0.89 | CTSK (0.40) | CTSKCTSSCTSVCTSLUSP30 | |
| SCHEMBL4041519 | 0.86 | CTSK (0.42) | CTSKCTSSCTSVCTSLCTSB | |
| SCHEMBL4043485 | 0.84 | CTSK (0.41) | CTSKCTSSCTSVCTSLUSP30 | |
| SCHEMBL4039009 | 0.84 | CTSK (0.41) | CTSKCTSSCTSVCTSLUSP30 | |
| SCHEMBL4039467 | 0.84 | CTSK (0.41) | CTSKCTSSCTSVCTSLUSP30 | |
| SCHEMBL6212766 | 0.83 | CTSK (0.40) | CTSKCTSSCTSVCTSLUSP30 | |
| SCHEMBL4040938 | 0.82 | CTSK (0.40) | CTSKCTSSCTSVCTSLUSP30 | |
| SCHEMBL4042823 | 0.82 | CTSK (0.40) | CTSKCTSSCTSVCTSLUSP30 | |
| SCHEMBL4044330 | 0.81 | CTSK (0.41) | CTSKCTSSCTSVCTSLUSP30 | |
| SCHEMBL4040930 | 0.81 | ACE (0.40) | CTSKCTSSCTSVCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | claimed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | claimed |
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |