Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 4/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 4/20 | 0.33 |
| ▸ | DRD4 | P21917 | 4/20 | 0.33 |
| ▸ | CTSV | O60911 | 2/20 | 0.33 |
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6209435 | 0.89 | CTSK (0.42) | CTSKCTSSCTSBUSP30CTSV | |
| SCHEMBL4040158 | 0.85 | CTSK (0.41) | CTSKHPGDSCTSSCTSBCTSV | |
| SCHEMBL4042759 | 0.84 | CTSK (0.39) | CTSKHPGDSCTSSCTSBUSP30 | |
| SCHEMBL4040456 | 0.83 | CTSK (0.39) | CTSKHPGDSCTSSCTSBDPP4 | |
| SCHEMBL4045112 | 0.83 | CTSK (0.40) | CTSKHPGDSCTSSCTSBUSP30 | |
| SCHEMBL6211330 | 0.82 | CTSK (0.38) | CTSKHPGDSCTSSCTSBUSP30 | |
| SCHEMBL6211156 | 0.81 | CHRM4 (0.41) | DPP4PREPCHRM4DRD2DRD4 | |
| SCHEMBL4040459 | 0.81 | CTSK (0.39) | CTSKHPGDSCTSSCTSBUSP30 | |
| SCHEMBL4041118 | 0.81 | CTSK (0.39) | CTSKHPGDSCTSSCTSBDPP4 | |
| SCHEMBL4039089 | 0.81 | CTSK (0.39) | CTSKHPGDSCTSSCTSBUSP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | claimed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | claimed |