Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 2/20 | 0.53 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.50 |
| ▸ | PNMT | P11086 | 3/20 | 0.46 |
| ▸ | CD44 | P16070 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5964226 | 0.94 | ASIC3 (0.60) | ASIC3CD274PNMTCD44MAOB | |
| SCHEMBL5963998 | 0.88 | AR (0.49) | ASIC3CD274AR | |
| SCHEMBL18554655 | 0.81 | CD274 (0.53) | ASIC3CD274PNMTCD44MAOB | |
| SCHEMBL7743680 | 0.78 | CD274 (0.72) | CD274PNMTCD44MAOBADRA2A | |
| SCHEMBL1105049 | 0.77 | HTR2C (0.55) | ADRA2AADRA2BADRA2C | |
| SCHEMBL1095278 | 0.77 | HTR2C (0.55) | ADRA2AADRA2BADRA2C | |
| SCHEMBL1095280 | 0.77 | HTR2C (0.55) | ADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL7746004 | 0.77 | CD274 (0.71) | CD274PNMTCD44MAOBADRA2A | |
| SCHEMBL2675790 | 0.76 | ASIC3 (0.67) | ASIC3PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL18554737 | 0.75 | ASIC3 (0.51) | ASIC3CD274PNMTCD44MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594856-A1 | CB 1/CB 2 RECEPTOR LIGANDS AND THEIR USE IN THE TREATMENT OF PAIN | AstraZeneca AB (SE) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004060882-A1 | CB 1/CB 2 RECEPTOR LIGANDS AND THEIR USE IN THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2004-07-22 | — | — | WO | disclosed |