SCHEMBL10022964

SCHEMBL10022964

CC(c1ccc(COc2ccc(-c3ccccc3)cc2)cc1)c1ccc(COc2ccc(-c3ccccc3)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GSTP1 P09211 2/20 0.58
FFAR1 O14842 3/20 0.56
ACACB O00763 1/20 0.54
BCHE P06276 2/20 0.51
RXRA P19793 1/20 0.51
RXRB P28702 1/20 0.51
ENPP3 O14638 1/20 0.50
ENPP1 P22413 1/20 0.50
ALOX5 P09917 1/20 0.49
SIGMAR1 Q99720 1/20 0.49
MAOB P27338 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10022963 1.00 GSTP1 (0.58) GSTP1FFAR1ACACBBCHERXRA
SCHEMBL14118337 0.86 BCHE (0.55) GSTP1FFAR1ACACBBCHEALOX5
SCHEMBL6721888 0.86 BCHE (0.55) GSTP1FFAR1ACACBBCHEALOX5
Biphenyl SCHEMBL9839827 0.84 ACACB (0.59) GSTP1FFAR1ACACBENPP3ENPP1
SCHEMBL9121973 0.82 ACACB (0.60) GSTP1FFAR1ACACBENPP3ENPP1
SCHEMBL23665904 0.82 GSTP1 (0.68) GSTP1FFAR1BCHEMAOB
SCHEMBL1096817 0.82 LMNA (0.69) GSTP1FFAR1BCHEENPP3ENPP1
SCHEMBL12285274 0.82 GSTP1 (0.68) GSTP1FFAR1BCHEMAOB
SCHEMBL23483029 0.82 LMNA (0.69) GSTP1FFAR1BCHEENPP3ENPP1
SCHEMBL13140346 0.81 FFAR1 (0.68) GSTP1FFAR1ACACBRXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8932797-B2 Photoacid generators DOW GLOBAL TECHNOLOGIES LLC (US) 2015-01-13 US disclosed
US-8907122-B2 Method of preparing photoacid generating monomer ROHM AND HAAS ELECTRONIC MATERIAL LLC (US) 2014-12-09 US disclosed
US-8716518-B2 Photoacid generating monomer and precursor thereof ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2014-05-06 US disclosed
US-20120172555-A1 PHOTOACID GENERATING MONOMER AND PRECURSOR THEREOF DOW GLOBAL TECHNOLOGIES LLC 2012-07-05 US disclosed
US-20120172619-A1 METHOD OF PREPARING PHOTOACID GENERATING MONOMER ROHM AND HAAS ELECTRONIC MATERIALS LLC 2012-07-05 US disclosed
US-20120141939-A1 PHOTOACID GENERATORS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2012-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120141939-A1 PHOTOACID GENERATORS F10, GNG2, H1-0 GSTP1 1214/4885FFAR1 473/4885ACACB 2715/4885
US-20120172555-A1 PHOTOACID GENERATING MONOMER AND PRECURSOR THEREOF SULT1A1, SULT1E1, SULT2A1 GSTP1 1150/4885FFAR1 116/4885ACACB 4142/4885
US-20120172619-A1 METHOD OF PREPARING PHOTOACID GENERATING MONOMER POLL, SULT1A1, SULT1E1 GSTP1 777/4885FFAR1 655/4885ACACB 3411/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.